摘要
以肉桂酸和无水乙醇为原料、廉价的氨基磺酸/浓硫酸为协同催化剂、环己烷为带水剂,合成了肉桂乙酯,收率90.0%。反应的优化条件为:氨基磺酸/浓硫酸/肉桂酸/无水乙醇=1.9/1/9.1/31.8(物质的量之比),时间3 h。利用该优化条件,共合成了9种羧酸乙酯,包括芳香酸、脂肪酸、二元酸、不饱和酸的乙酯。该法突出的优点有:催化剂价廉易得且可重复使用、产率高、后处理简便。
Ethyl cinnamate was efficiently synthesized in 90. 0% isolated yield by using cinnamic acid and anhydrous ethanol as sub- strates, and amino sulphonic acid/concentrated sulfuric acid as synergistic catalyst. The optimized reaction conditions were ： amino sulphonic acid/concentrated sulfuric acid/cinnamic acid/anhydrous ethanol = 1.9/1/9. 1/31.8 （ molar ratio）, reaction time 3 h. Other eight ethyl carboxylates were easily synthesized under the optimized conditions, including aryl, aliphatic, diacid, and unsatu- rated acid ethyl esters. The method featured recyclable and cheap synergistic catalysts, excellent isolated yields as well as very con- venient reaction workup.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2014年第2期277-280,共4页
Chemical Research and Application
基金
国家自然科学基金项目(21264008)资助
江西科技师范大学本科生创新科研基金项目资助
关键词
协同催化
氨基磺酸
肉桂酸乙酯
羧酸乙酯
synergistic catalysis
amino-sulfonic acid
ethyl cinnamate
ethyl carboxylate
