摘要
目的:探讨环境湿度对微生态制剂质量的影响。方法:以微生态制剂地衣芽胞杆菌胶囊为研究对象,在模拟的高湿度环境中研究了其干燥失重、活菌数和崩解时限的变化。结果:在相对湿度为80%的环境中放置48 h后,药品的活菌数、干燥失重、崩解时限均有显著变化。结论:高湿对益生菌制剂质量有很大影响,该类制剂应严格遵循药品贮存和使用的条件,并注意密闭包装。
Objective： To study the influence of environment humidity to the probiotics. Methods： Taking Bacil lus licheniformis capsule as investigated subject, the changes of drying loss, survival number and disintegration time limit under a model high-humidity condition were observed. Results： Compared with normal conditions, the live bacteria number of the Bacillus licheniformis capsules were reduced significantly after 48 h on 80% humidity environment. Conclusion： The high humidity has significant impact on probiotie product. So probiotic product should be instriet accordance with the storage and use condition, and keep in tight packs.
出处
《生物技术通讯》
CAS
2014年第1期105-106,共2页
Letters in Biotechnology
关键词
地衣芽胞杆菌胶囊
湿度
质量
益生菌
Bacillus licheniformis capsules
humidity
quality
probiotic
