摘要
目的应用Ac_T5diff血细胞分析仪检测老年妇科肿瘤患者放疗后血象变化，以便及时消除骨髓抑制。方法收集经病理学检查确诊的宫颈癌放疗患者34例，年龄53～68岁，白细胞数下降至2．0×109／L后注射里亚金，采集外周血，EDTA抗凝，4h内应用Ac_T5diff血细胞分析仪监测计数血常规，采用SPSSl4．0统计学软件进行t检验。结果宫颈癌患者放疗后外周血白细胞下降至（1．7±1．1）×109／L，注射里亚金后5d升至（5．8±4．1）×109／L，明显高于用药前，差异有统计学意义（P〈0．01）；中性粒细胞也明显上升（P〈0．01）。对Ac_T5d珂血细胞分析仪检测的单核细胞、嗜酸出位细胞和嗜碱性粒细胞数异常的病例，应用传统人工镜检方法计数，两种方法计数结果差异无统计学意义（P〉0．05）。结论Ac_T5diff血细胞分析仪可标准化、快速监测宫颈癌放疗患者血细胞变化。
Objective To observe ther blood changes in elderly patients with gynecologic cancers after radiotherapy. Methods Thirty-four 53-68 year old cases pathologically diagnosed with cervical cancer and received radiotherapy were collected. Maria Kim was injected into the cases after white blood cell count decreased to 2.0 × 109/L,then blood samples were collected and added in EDTA as anticoagulant. Ac_TSdiff hematology analyzer was used within four hours to monitor and count blood cells,and SPSS14.0 statistical software was applied for t test. Results After radiotherapy, WBC of cervical cancer patients was decreased to（ 1.7 ± 1.1 ） × 109/L, and increased to（5.8 ±4.1 ） × 109/L five days after injecting Maria Kim, significantly higher than that before treatment, showing statistically significant （P〈0.01）and the level of neutrophils was also increased significantly （P〈0.01）. The abnormal count of monocytes, eosinophils and basophils in cancer cases determined by Ac_TSdiff hematology analyzer was coincident with that detected by traditional manual microscopic counting method （P〉0. 05）. Conclusions Ac_TSdiff hematology analyzer can be used for standardized and rapid monitoring of blood changes in cervical cancer patients receiving radiotherapy.
出处
《中国热带医学》
CAS
2013年第12期1553-1555,共3页
China Tropical Medicine
