摘要
目的探讨肌红蛋白(Mb)、心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶MB型(CK-MB)联合检测在急性冠状动脉综合征(ACS)诊断中的价值。方法选取85例ACS患者[其中不稳定型心绞痛(UA)25例、心肌梗死60例]作为ACS组,除ACS外的冠心病(CHD)患者68例作为CHD组,60例健康体检者作为健康组进行血清Mb、cTnI、肌酸激酶(CK)、CK-MB检测,并进行统计学分析和评价。结果 ACS组患者血清Mb、cTnI、CK-MB水平均高于CHD组及健康组,差异有统计学意义(P<0.05)。结论血清Mb是ACS诊断中敏感且较特异的生化指标,Mb、cTnI、CK-MB联合检测有助于ACS早期的快速诊断和鉴别诊断,具有重要的临床意义。
Objective To investigate the clinical significance of myoglobin（Mb） combined with creatine kinase isoenzyme MB （CK-MB） and cardiac troponin I （cTnI） in the diagnosis of acute coronary syndrome（ACS）. Methods 85 patients with acute coro- nary syndrome and 68 patients with coronary heart disease（CHD） were included in disease group in the study. 60 healthy individu- als were selected as controls. Then Mb,CK-MB and cTnI were detected. All data were analyzed statistically by SPSS 16.0. Results The Mb,CK-MB and cTnI levels in ACS patients were all significantly higher than those in control group（P〉0.05）. Conclusion Myoglobin is a sensitive and specific biochemical indicator for the diagnosis of acute coronary syndrome. Myoglobin combined with CK-MB and cTnI is helpful for the diagnosis of acute coronary syndrome.
出处
《国际检验医学杂志》
CAS
2014年第3期267-268,共2页
International Journal of Laboratory Medicine
基金
国家高技术研究发展计划("863"计划)基金资助项目(2011AA02A111)
