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Formulation of an Early Warning Infectivity Score System for Adult Patients with Acute Bacterial Diarrhea 被引量:1

Formulation of an Early Warning Infectivity Score System for Adult Patients with Acute Bacterial Diarrhea
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摘要 The aim of our study was to develop a scoring system to predict whether diarrhea is of a bacterial origin and whether the diarrheal patients constitute a potential source of infection to others. Adults with acute diarrhea (n=424) were enrolled in the study. Logistic regression and standard regression coefficients were used to formulate the Early Warning Infectivity Score System for Adults with Acute Bacterial Diarrhea (EWIS-ABD). Four risk factors were identified by logistic regression, including body temperature (P〈0.01), abdominal pain (P〈0.01), leukocyte count in stool (P〈0.01), and unclean dietary history (P〈0.01). EWIS-ABD was thus developed, in which the value 〉5 points was set as an indicator of bacterial diarrhea. The incidence of bacterial diarrhea increased along with the elevated score. EWIS-ABD was more specific for bacterial diarrhea than for viral diarrhea. The accuracy and reliability of EWIS-ABD was high by prospective validation in 478 patients with acute diarrhea. The aim of our study was to develop a scoring system to predict whether diarrhea is of a bacterial origin and whether the diarrheal patients constitute a potential source of infection to others. Adults with acute diarrhea (n=424) were enrolled in the study. Logistic regression and standard regression coefficients were used to formulate the Early Warning Infectivity Score System for Adults with Acute Bacterial Diarrhea (EWIS-ABD). Four risk factors were identified by logistic regression, including body temperature (P〈0.01), abdominal pain (P〈0.01), leukocyte count in stool (P〈0.01), and unclean dietary history (P〈0.01). EWIS-ABD was thus developed, in which the value 〉5 points was set as an indicator of bacterial diarrhea. The incidence of bacterial diarrhea increased along with the elevated score. EWIS-ABD was more specific for bacterial diarrhea than for viral diarrhea. The accuracy and reliability of EWIS-ABD was high by prospective validation in 478 patients with acute diarrhea.
出处 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第1期65-69,共5页 生物医学与环境科学(英文版)
基金 funded by the National Key Technology R&D Program during the Eleventh 5-year Plan Period[2007BAI24B06]
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