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斑块内新生血管的作用及应对 被引量:7

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摘要 斑块内新生血管是由内皮细胞芽生形成。动脉粥样硬化相关的生理性新生血管能改善动脉壁供氧状态,减轻炎症反应,逆转动脉粥样硬化的进展。病理性新生血管则会加速疾病的进程,增加巨噬细胞浸润和血管壁的厚度,导致持续的缺氧状态,甚至坏死。此外,新生血管壁的破裂可以导致斑块内出血、增强炎性反应、扩大脂质核心、激发氧化应激反应和斑块破裂。
作者 郗扬
出处 《国际心血管病杂志》 2014年第1期14-17,共4页 International Journal of Cardiovascular Disease
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