摘要
目的通过体外基础研究探讨不同大小的引流管对不同性质液体的引流效果，确定能满足临床上胸腔引流需要的引流管大小。方法体外实验把1000mL30％血球压积的全血、2．5％白蛋白溶液、0．9％生理盐水分成A、B、C三组，分别用管径为6F（French，F）、8F、10F、12F、14F、16F、18F、20F、22F、24F、26F、28F、30F、32F、34F、36F引流管进行重复引流，计算引流量。相同性质液体采用不同大小引流管的引流量之间的比较采用单因素方差分析，不同性质液体采用不同大小引流管的引流量之间的多重比较采用双因素方差分析，并遵照泊肃叶公式进行曲线拟合。结果三组液体的引流量与引流管大小成正相关，双因素方差分析中6F与8F引流管差异无统计学意义（P=0．513），其他大小引流管多重比较，差异有统计学意义（P〈0．05）；A组引流量数据单因素方差分析中，与引流量为3．33mL／min的对照值比较，6F和8F引流管引流量大于3．33mL／min，但差异无统计学意义（P〉0．05），10F及以上的引流管的引流量明显大于对照值（P〈0．05）。拟合曲线方程分别为：A组Q=o．0029X4，R2=0．991；B组Q=0．0032X4，R4=0．981；C组引流量Q=0．0034X4，R2=0．975。当Q=3．33时，A组引流量拟合曲线方程中X=5．82F。结论本基础实验研究提示小管径引流管（6F～14F）理论上可以满足临床上对血胸、渗出液及漏出液的引流。
Objective To determine the appropriate size of the tube for the thoracic drainage in good efficiency by the experimental study in the influence of the tube size on the flow rate of the fluid with different properties. Methods Three groups were divided according to the different components in the fluid： group A, whole blood with 30% hematocrit; group B, 2. 5% albumin solution; and group C, O. 9% normal saline. The total volume of the fluid was 1000 mL in each group in the experiment. Different sorts of fluids were drained with the chest tubes with different diameters （6F, 8F, 10F, 12F, 14F, 16F, 18F, 2OF, 22F, 24F, 26F, 28F, 30F, 32F, 34F, 36F of French F） separately, and the flow rate was calculated. ANOVA was used for the comparison of the differences in flow rate among the groups with given fluid property. Two- factor analysis of variance was used for the analysis of flow rates of fluid with different fluid properties. Curve fitting was performed according to the Poiseuille formula. Results The flow rate was positively correlated with the size of the chest drainage tube. The difference in flow rate among the tubes with difference in size was statistically significant （P 〈0. 05） but there was no noticeable difference in flow rate between 6F and 8F （P =0. 513）. The flow rate of the 6F and 8F tubes was higher than that of the control （3.33 mL/min） but there was no significant difference between them （P 〉 0. 05 ）. The flow rate of the tubes in IOF and above was obviously higher than that of control （ P 〈 0. 05 ）. The curve was estimated that group A was Q = 0. 002 9X4, R2 =0.991; group B Q =0.003 2X4, R2 =0.981; group C Q =0.003 4X4, R2 =0.975. When theflow rate was fixed at 3.33 mL/min, the estimated curve in group A was X ~ 5.82F. Conclusions Our experiment indicated that the chest tube with small diameters （6F - 14F） could meet the demand of high efficient drainage in the patients with hemothorax or pleural effusion.
出处
《中华急诊医学杂志》
CAS
CSCD
北大核心
2014年第1期45-49,共5页
Chinese Journal of Emergency Medicine
基金
浙江省卫生厅基金资助（G20060694）
浙江省教育厅科研项目（Y201018337）
浙江省医药卫生一般研究计划（2012KYB092）
