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预防对化疗导致的恶心和呕吐的药物临床研究设计的考虑要点 被引量:9

Considerations on the clinical study design of the drugs for the prevention of nausea and vomiting associated with cancer chemotherapy
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摘要 化疗是治疗恶性肿瘤的一种重要方法,但化疗可引起多种不良反应,最为常见的就是恶心和呕吐。本文简要介绍了预防化疗恶心和呕吐药物临床研究设计的考虑要点,旨在为此类新药的研发提供参考。 Chemotherapy induced nausea and vomiting is one of the most frequently reported adverse events in patients receiving chemotherapy. The article briefly describes the considerations on the clinical study de- sign of the drugs for the prevention of nausea and vomiting associated with cancer chemotherapy in order to provide a reference for research and de- velopment of these new drugs.
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2014年第1期70-72,共3页 The Chinese Journal of Clinical Pharmacology
关键词 止吐药 临床研究 恶心 呕吐 antiemetic drug clinical study nausea vomiting
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参考文献2

  • 1EMA. Guideline on non-clinical and clinical development of medical products for the prevention of nausea and vomiting associated with cancer chemotherapy[EB/OL].http://www.ema.europa.eu/ema/pages/includes/document/open_document.jsp?webContentId=WC500017745,2006. 被引量:1
  • 2NCCN. Antiemesis,Version 1.2014[EB/OL].http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#antiemesis,2013. 被引量:1

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