摘要
复发性流产(recurrent spontaneous abortion,RSA)一般指与同一配偶发生连续3次或3次以上的自然流产。近年来许多学者提出将连续发生2次的自然流产者纳入RSA的范畴,原因是连续发生2次自然流产后,再次妊娠的流产率可高达50%以上,要引起足够的重视。RSA的病因复杂,目前已知的病因有染色体异常、生殖道解剖异常、内分泌失调、感染性疾病因素、血栓前状态、自身免疫因素等。除此之外,临床上仍有至少40%以上的患者病因不明。由于RSA的病因复杂,造成了RSA的难治性,是目前基础与临床研究的难点与热点。
Recurrent spontaneous abortion （RSA） is defined as the occurrence of three or more consecu- tive abortions with the same partner. Scholars in re- cent years have proposed that two consecutive sponta- neous miscarriages should be included in the scope of RSA, because the abortion risk for future pregnancy is up to 50%, the clinical manifestation should be paid more attentionnow. RSA is a complex multifac- torial problem associated with chromosome, repro- ductive tract anatomic, endoerinologic, infection, immune etiologies and pre-thrombotic state, but asu- bstantial proportion of RSA, up to 40%, are due to unexplained or unknown etiologies. The complex eti- ology made RSA one of diseases to be treated diffi- culty and a hot spots in the present clinical research work.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2014年第1期41-45,共5页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
复发性流产
病因学
recurrent spontaneous abortion
etiology
