摘要
目的分析研究宫外孕患者运用米非司酮联合甲氨蝶呤予以治疗的临床作用,探讨理想的治疗方法。方法将2012年1月—2013年1月期间经该院妇科确诊的120例宫外孕患者设为研究对象,并将其随机均分为研究组和对照组各60例。研究组给予米非司酮联合甲氨蝶呤(MIX)予以治疗,而对照组则单一给予甲氨蝶呤注射治疗。观察两组患者的促性腺激素(β-HCG)指标情况,以及不良反应发生情况。结果研究组治疗有效率为82.6%,而对照组的治疗有效率为53.5%,实验组疗效明显高于对照组,差异有统计学意义(P<0.05),研究组不良反应、并发症情况发生率为10.0%,对照组不良反应、并发症情况发生率为11.7%,差异无统计学意义(P>0.05)。结论针对宫外孕患者运用米非司酮联合甲氨蝶呤疗效较单一用药更为理想,且安全性更佳,患者满意度高,故具有显著的临床推广价值。
Objective To investigate the effect of Mifepristone and Methotrexate in the treatment of patients with ectopic pregnancy, and summarize the ideal treatment method for the disease. Methods 120 cases of patients diagnosed with ectopic pregnancy in Department of Gynaecology of our hospital from January, 2012 to January, 2013 were set as the research objects. And they were randomly divided into study group and control group with 60 cases in each. The study group was given Mifepristone combined with Methotrexate(MIX) therapy, while the control group was given methotrexate injection therapy. The gonadotrophin(β-HCG) index and the occurrence of adverse reactions of two groups were observed. Results The effective rate of the study group was 82.6%, significantly higher than the control group's 53.5%, the difference was statistically significant(P <0.05); the adverse reactions and complications incidence was 10.0% in the study group, and 11.7% in the control group, the difference was not statistically significant(P> 0.05). Conclusion For patients with ectopic pregnancy, mifepristone combined with methotrexate are more effective and safe than single medication with high patient satisfaction, which have a significant value of clinical promotion.
出处
《中外医疗》
2013年第36期94-95,共2页
China & Foreign Medical Treatment
关键词
米非司酮
甲氨蝶呤
宫外孕
效果研究
Mifepristone
Methotrexate
Ectopic pregnancy
Effect study
