摘要
目的探讨轻型弥漫性轴索损伤(DAI)的临床特征与诊治方法。方法回顾性分析10例轻型DAI患者的临床资料。结果10例患者均有昏迷史,昏迷时间10 min～6 h。头颅CT检查结果示7例未见异常,2例头皮血肿,1例少量蛛网膜下腔出血,未见脑实质内出血和颅内血肿。伤后24 h内MRI检查结果示10例均发现2～6 mm大小的脑内损伤灶,每例1～5个,平均3.2个。出院后10例患者随访1～5年,无死亡和严重残疾病例;8例遗留不适症状;2例恢复正常,无不适症状。10例患者GOS评分均为5分。结论头部MRI诊断轻型DAI敏感性优于头部CT;加强认识可以早期诊断和治疗,多数患者预后良好。
Objective To explore the clinical features, early diagnosis and treatment of mild diffuse axonal injury （mDAI）. Methods The clinical data of 10 patients with mDAI admitted to our hospital from May 2008 to May 2012 were retrospectively analyzed. All patients were received conservative treatment. All patients were followed up for 1-5 years. Results Coma lasting 10 minutes to 6 hours occurred in all patients after trauma. The computed tomography obtained 0.5-3 hours after trauma showed normal in 7 patients, scalp hematoma in 2 and small subarachnoid hemorrhage in 1. The magnetic resonance imaging obtained whining 24 hours after trauma showed scattered lesions （1-5 lesions per patient with an average of 3.2 lesions; diameter, 2-6 mm） which presented with high signal intensity on T1- and T2-weighted images, fluid-attenuated inversion recovery images and diffusion-weighted images in all patients. No death and severe disability occurred during the follow up. Conclusions The magnetic resonance imaging is more sensitive than the computed tomography in diagnosing mDAI. Most patents with mDAI can achieve good outcome.
出处
《中国临床神经外科杂志》
2013年第12期731-733,共3页
Chinese Journal of Clinical Neurosurgery
关键词
轻型弥漫性轴索损伤
临床特征
诊断
治疗
Mild diffuse axonal injury
Early diagnosis
Clinical characteristic
