摘要
目的对阿莫西林与阿莫西林-克拉维酸钾导致的不良反应进行比较和研究。方法选取我院收治的164例患者,分为观察组和对照组各82例,观察组患者接受阿莫西林治疗,对照组患者接受阿莫西林-克拉维酸钾治疗。对两组患者的治疗情况进行跟踪和观察。结果所有患者均出现了不同程度的不良反应,比较两组出现不良反应患者的性别和年龄,没有显著差异(P>0.05)。两组患者出现的各项不良反应例数均存在显著差异(P<0.05)。经治疗,观察组中3例(3.7%)、对照组中1例(1.2%)患者的不良反应对患者疾病产生了显著影响,两组差异显著(P<0.05)。结论阿莫西林-克拉维酸钾比阿莫西林不良反应小,较为安全,值得在临床推广应用。
Objective To amoxicillin and amoxicillin-clavulanate potassium cause adverse reactions to compare and research.Methods Select our hospital, 164 patients were divided into observation group and control group, 82 cases in the observation group patients receiving amoxicillin treatment and control group patients received amoxicillin-clavulanate potassium treatment. Treatment of two groups of patients to track and observation. Results All patients experienced varying degrees of adverse reactions, adverse reactions were compared with gender and age, no significant difference （P〉0.05）. Two groups of patients with various number of cases of adverse reactions, there were significant differences （P〈0.05）. After treatment, the observation group, 3 patients （3.7%） in the control group, 1 case （1.2%） adverse reactions in patients with the disease on patients had a significant impact, the difference was significant （P〈0.05）. Conclusion The use of amoxieillin-clavulanate potassium treatment than amoxicillin adverse reactions in clinical use should be based on specific indications, contraindications excluded, and thus play the efficacy of drugs due.
出处
《中国医药指南》
2013年第36期340-341,共2页
Guide of China Medicine
