摘要
目的：比较卵巢癌不同发病年龄、体重指数（BMI）、孕产次、病理分类、组织学分级、二元论分型中输卵管结扎的比例,探讨输卵管结扎对卵巢癌的影响。方法：选取2001年6月-2013年2月在郑州大学第三附属医院和郑州大学第一附属医院妇产科就诊的189例卵巢癌患者,同期选取因子宫肌瘤、子宫脱垂就诊的209例患者作为对照组,比较两组患者的输卵管结扎比例。结果：189例卵巢癌患者中89例行输卵管结扎,209例对照组中99例行输卵管结扎。卵巢癌患者中≤44岁者的输卵管结扎比例显著低于对照组（P〈0.05）;BMI为18.5-24.9kg/m^2和≥25kg/m^2者的输卵管结扎比例与对照组比较,均无显著差异（P〉0.05）;孕产1-2次者输卵管结扎比例低于对照组（P〈0.05）,≥3次者的输卵管结扎比例显著高于对照组（P〈0.05）。卵巢浆液性癌、黏液性癌和子宫内膜样癌患者中,行输卵管结扎的比例分别为44.4%（48/108）、52.5%（32/61）和45.0%（9/20）。卵巢癌不同病理类型间的输卵管结扎比例无显著差异（P=0.593）。卵巢癌G1、G2、G3级患者中,行输卵管结扎的比例分别为50.0%（52/104）、50.9%（29/57）和28.6%（8/28）,无显著差异（P=0.104）;但G3级显著低于G1＋G2组（P=0.033）。二元论分型Ⅰ、Ⅱ型中行输卵管结扎比例分别为50.0%（52/104）和43.5%（37/85）,无显著差异（P=0.375）。结论：卵巢癌的发病机理、组织起源等可能与输卵管结扎有关。
Objective ：To compare the proportion of tubal ligation in ovarian cancer on-set ages, body mass index （ BMI）, maternal times, different pathologic classification, histological grade and dualism typing, and to understand the effect of tubal ligation on ovarian cancer. Methods：Retrospective analysis of 189 cases of ovarian cancer patients in the department of Obstetrics and Gynecology of the Third Hospital Affiliated to Zhengzhou University and the First Hospital Affiliated to Zhengzhou University from June 2001 to Feb. 2013. Select 209 cases pa-tients due to hysteromyoma or uterine prolapse as a control group. We compared the proportion of tutal ligation between the two groups. Results：The tubal ligation patients in ovarian cancer group （189 patients） and the control group （209 patients） were 89 and 99 respectively. The ratio of the tubal ligation patients aged ≤44 years was lower than that of the control group （ P〈 0.05）. There was no significant difference between the BMI 18.5 -24.9kg/m^2/≥25kg/m^2 and the control group （P〉0.05）. The ratio for maternal 1 - 2 times group was lower than the control group （P〈0.05）. Tubal ligation was 48 cases （44.4%） in 108 cases of ovarian serous carcinoma,32 cases （52. 5%） in 61 cases of ovarian mueinous carcinoma and 9 cases （45.0%） in 20 cases of ovarian endometrial carcinoma. In G1 , G2, G3 grade of ovarian cancer, tubal ligation was 52 cases,29 cases,8 cases respectively. 52 cases were tubal ligation in dual-ism parting type Ⅰ and 37 cases were tubal ligation in type Ⅱ. Conclusion：Tubal ligation may have a certain effect on the pathogenesis and tissue origin of ovarian cancer.
出处
《现代妇产科进展》
CSCD
2013年第12期983-985,共3页
Progress in Obstetrics and Gynecology
关键词
卵巢癌
输卵管结扎
二元论
Ovarian cancer
Tubal ligation
Dualism
