摘要
目的:用组织多普勒(TDI)测定Tei指数评估类风湿性关节炎患者(RA组)的左心室整体功能受损情况。方法:选取类风湿性关节炎患者60例,另选取56例性别、年龄相匹配的健康人作为对照组,采集二尖瓣环后间隔、侧壁、前间隔、后壁、前壁、下壁6个位点的组织运动速度曲线,测量上述6个位点的收缩期峰值速度(Sa)、舒张早期峰值速度(Ea)、舒张晚期峰值速度(Aa),计算舒张早、晚期峰值速度比值(Ea/Aa),均取6个位点各指标的平均值。同时测量各位点Tei指数并取平均值。结果:RA组与正常对照组相比,Ea峰、Aa峰、射血分数两组之间未见明显差异(P>0.05),而RA组二尖瓣环Sa峰、Ea/Aa比值降低(P<0.05),Tei指数升高(P<0.05)。结论:RA可导致左心室舒张和收缩功能降低,组织多普勒技术测定Tei指数是一理想的评估RA患者左室整体功能的方法。
Aim：To assess left ventricular function using Tei Index by Tissue Doppler Imaging in pa-tients with rheumatoid arthritis （RA）.Methods：Sixty patients with RA and 56 healthy persons were in-cluded in this study.Tissue movement curves of Mitral annulus were collected by TDI.peak systolic ve-locity（Sa）,peak early diastolic velocity（Ea）,peak end diastolic velocity（Aa）were measured,and Ea/Aa ratio were calculated.Tei index was also calculated from the results of TDI.Results：mitral annular Sa,Ea/Aa decreased （P0.05 ）.Conclusion：Left ventricular dysfunction in patients with RA was caused by both di-astolic function and systolic function reduced.The Tei index come from TDI is an ideal indicator to assess left ventricular function in patients with RA.
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
北大核心
2013年第6期646-648,654,共4页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
广东医学科研基金项目(A2007343)
关键词
组织多普勒
类风湿性关节炎
左心室舒张功能
左心室收缩功能
TEI指数
Doppler tissue imaging
rheumatoid arthritis
ventricular diastolic function
ven-tricular systolic function
Tei index
