摘要
目的了解脑出血急性期常规生化指标改变与患者预后的相关性。方法回顾性分析113例脑出血急性期患者,根据其预后状况良好与否分为研究组(n=52)和对照组(n=61);以68例健康者作为健康组。检测其血总胆固醇、三酰甘油、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、血糖及尿酸水平。结果 3组受检者血总胆固醇和三酰甘油的差异无统计学意义(P>0.05),研究组患者血LDL-C、血糖明显高于健康组(P<0.05),对照组患者血HDL-C、血尿酸及血糖明显高于研究组(P<0.05)。将总胆固醇、三酰甘油、LDL-C、HDL-C、血尿酸、血糖及年龄这7个变量作为自变量,以患者预后作为因变量,建立Logistical回归方程,分析显示年龄、HDL-C、血尿酸、血糖是急性期脑出血不良预后的危险因素。结论高龄、HDL-C、血尿酸、血糖可作为脑出血预后不良的预测性指标。
Objective To understand the correlation of conventional biochemical indexes change at acute stage with prognosis of patients with hemorrhage.Methods 113 patients with acute cerebral hemorrhage were retrospectively analyzed,and were divided into study group（patients with good prognosis,n=52） and control group（patients with poor prognosis,n=61） according to the prognosis.68 healthy people served as healthy group.Their blood total cholesterol,triglycerides,low density lipid-cholesterol（LDL- C）,high density lipid-cholesterol（HDL-C）,glucose and uric acid were detected.Results Differences of blood total cholesterol and triglycerides of patients among three groups showed no statistically significant（P〈0.05）.LDL-C and blood glucose of patients in the study group were markedly higher than those in healthy group（P〈0.05）.HDL-C,serum uric acid and blood glucose of patients in the control group were obviously higher than those in the study group（P〈0.05）.The total cholesterol,triglycerides,LDL-C, HDL-C,uric acid,glucose and age were served as independent variables,and the prognosis of patients as dependent variable,Logisti- cal regression equation was established and demonstrated that age,HDL-C,uric acid,glucose were risk factors of poor prognosis of acute hemorrhage.Conclusion Advanced age,HDL-C,serum uric acid,blood glucose may be predictive indicators of poor prognosis of hemorrhage.
出处
《国际检验医学杂志》
CAS
2013年第23期3151-3153,共3页
International Journal of Laboratory Medicine
关键词
脑出血
血糖
尿酸
预后
血脂
cerebral hemorrhage
blood glucose
uric acid
prognosis
blood lipids
