摘要
目的探讨短程放疗治疗宫颈癌患者摆位改变对膀胱和直肠HR-CTV D90的影响。方法接受外照射和高剂量率ICBT治疗的58例宫颈癌患者纳入研究,采用其中一种ICBT,行盆腔CT扫描并采集HR-CTV数据。这些病例分为标准剂量组和适应剂量组(覆盖HR-CTV照射6Gy等剂量线)。每个过程评估HR-CTV D90和摆位改变。结果标准剂量组前三次ICBT的HR-CTV D90随摆位改变呈递增趋势,而适应剂量组相对恒定。结论肿瘤体积摆位改变和影像引导的适应性短程放疗可在膀胱和直肠能接受的范围内改善HR-CTV剂量选择。
Objective To expolre the effect of interfractional changes on HR-CTV D90 during brachytherapy for uterine cervical cancer patients. Methods 58 patients received EBRT and HDR ICBT. For one ICBT applications, a pelvic CT scan was performed and the HR-CTV was recorded. These patients were divided into standard dose group and adaptive dose group.The HR-CTV D90 was evaluated and analyzed as interfractional changes. Results The interfractional changes of the HR-CTV D90 in the standard dose group showed an increase during former three times ICBT, those of the adaptive dose group remained almostly constant. Conclusion Image-guided adaptive brachytherapy based on interfractional tumor volume change might improve the dose to the HR-CTV.
出处
《中国医药科学》
2013年第23期75-76,共2页
China Medicine And Pharmacy
