摘要
目的:分析2012年1-12月我院重症监护病房(ICU)鲍曼不动杆菌感染/定植情况,为临床治疗鲍曼不动杆菌感染提供参考。方法:采用回顾性研究方法,查阅临床资料和临床微生物检测报告,分析我院ICU重症患者鲍曼不动杆菌感染/定植情况及治疗结局。结果:2012年1-12月我院ICU收治的重症患者中共检出鲍曼不动杆菌107例,确定为鲍曼不动杆菌感染85例(79.4%),确定为鲍曼不动杆菌定植22例(20.6%)。其中21例(19例感染,2例定植)患者因基础病难以逆转或经费困难放弃治疗。纳入研究的66例鲍曼不动杆菌感染患者中,59例(89.4%)患者为泛耐或全耐鲍曼不动杆菌感染,7例(10.6%)为敏感鲍曼不动杆菌感染。确定为感染的66例患者均按照《中国鲍曼不动杆菌感染诊治与防控专家共识》的推荐意见,给予舒普深+米诺环素/舒普深治疗,其中50例(75.8%)患者感染控制转出ICU,16例(24.2%)患者死亡,死亡患者中确定死于鲍曼不动杆菌感染的患者2例(3.0%)。结论:①鲍曼不动杆菌致病力较弱;②根据专家共识对鲍曼不动杆菌感染进行治疗,有效率较高。
Objective： To investigate outcomes of critically ill patients with acznetobacteroaurnannzz ~. baumannii） infection/colonization in intensive care unit （ICU）, and to provide clinical experience for the management of such patients. Methods- Clinical data concerning A. baumannii infection/ colonization among critically ill patients in our ICU were collected and analyzed retrospectively. Outcomes of these patients were also studied. Results： A. baumannii was detected from 107 ICU patients hospitalized between January 2012 and December 2012. Among them, 85 cases（79.4~） were identified as A. baumannii infection, and 22 （20.6%） cases were identified as A. bauman- nii colonization. 21 cases （infection, 19 cases; colonization, 2 cases） of them were excluded from this study because of treatment abandonment. All of the sixty-six cases with A. baumannii infec- tion were treated with sulperazone or sulperazone＋minocycline according to China Experts Con- sensus about Managements of Acinetobacter Baumannii Infection. 50 cases（75, g %） with A. bau- mannii infection were cured and transferred out of 1CU. The number of deaths was 16（24. 2%）, and only 2 cases （3.0%） died of A. baumannii infection. Conclusion： Pathogenicity of A. bau- mannii is weak, and most of infection cases can be cured according to the experts consensus.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2013年第6期895-898,共4页
Medical Journal of Wuhan University
关键词
鲍曼不动杆菌
感染
定植
治疗
AcinetobacterBaumannii
Infection
Colonization
Treatment
