摘要
目的探讨血清降钙素原(PCT)、C反应蛋白(CRP)、白细胞(WBC)测定在儿童感染性疾病中的临床意义。方法将住院的84例患儿分成细菌感染、病毒感染和非感染对照三组,检测各组血清PCT、CRP、WBC的含量,并对各指标表达量和阳性率进行比较。结果细菌感染组和病毒感染组PCT分别为7.81±12.51,0.31±0.45,两组含量差异有统计学意义(P<0.05);WBC在两组表达量分别为15.24±6.06,10.88±4.68,两组比较差异有统计学意义(P<0.05),CRP在两组含量分别为28.03±31.91,15.46±19.35,两组比较差异无统计学意义(P>0.05)。PCT在细菌组、病毒组、非感染组阳性率比较差异有统计学意义(P<0.01);CRP在细菌组和病毒组阳性率比较差异无统计学意义(P>0.05),对照组和其他两组间比较差异有统计学意义(P<0.05);WBC在对照组和病毒组阳性率比较差异无统计学意义(P>0.05),细菌组和其他两组间比较差异有统计学意义(P<0.05)。结论血清PCT可作为儿童感染性疾病的鉴别诊断与早期诊断的有效指标。
Objective To explore the clinical diagnostic value of procalcitonin（PCT）, C-reaction protein （CRP）and white blood cell （WBC）in bacterial infections in children. Methods Eighty four cases （children） from the hospital were divided into three groups by clinical diagnosis., groups of bacterial infections, viral infections and control. The expression level and positive rate of PCT, CRP and WBC in different groups were determined. Results The level of PCT in the bacterial infections and viral infections was 7.81± 12.51 and 0. 31 ± 0. 45, with a statistically significant difference（P〈0. 05）. The level of CRP in the two groups were 28.03±31.91 and 15.46±19.35,with no significant difference. The levels of WBC in the two groups were 15.24±6.06 and 10.88±4.68, with a statistically significant difference （P〈0.05）. Positive rate of PCT between the bacterial infections, viral infections was statistically significant （P〈0.05）. For the WBC, positive rate was statistically significance between the bacterial infections and viral infections （P〈0. 05）. However, the positive rate of CRP was no statistically significant between the two groups. Conclusions PCT is a reliable laboratory index in the early diagnosis of bacterial infections in children.
出处
《临床输血与检验》
CAS
2015年第6期506-508,共3页
Journal of Clinical Transfusion and Laboratory Medicine
关键词
降钙素原
感染性疾病
细菌
病毒
C反应蛋白
白细胞计数
Procalcitonin Respiratory infection Bacteria Viral C-reaction protein White blood cell counts
