摘要
目的 确定1.5％利多卡因用于经尿道膀胱肿瘤电切术患者闭孔神经阻滞时的半数有效容量（EVs）.方法 选择拟行经尿道膀胱肿瘤电切术的膀胱侧壁肿瘤患者36例,术前均确定需行闭孔神经阻滞,ASA分级Ⅰ或Ⅱ级,BMI 19～ 30 kg/m2,年龄18 ～64岁,在周围神经刺激仪引导下经传统耻骨入路用1.5％利多卡因行闭孔神经阻滞,1.5％利多卡因容量根据序贯法确定,初始容量10 ml,相邻容量比值1.1.闭孔神经阻滞成功为阳性反应.计算1.5％利多卡因用于闭孔神经阻滞时的EV.及其95％可信区间（CI）.结果 1.5％利多卡因用于周围神经刺激仪引导下经耻骨入路闭孔神经阻滞时的EV50为5.53 ml,95％CI为5.10～6.00 ml.结论 1.5％利多卡因用于经尿道膀胱肿瘤电切术患者闭孔神经阻滞时的EV.为5.53 ml.
Objective To determine the effective volume of 1.5％ lidocaine for obturator nerve block （ONB） in 50％ of patients （EV50） undergoing transurethral resection of bladder tumor （TURBT）.Methods Thirty-six ASA physical status Ⅰ or Ⅱ patients with bladder tumor,aged 18-64 yr,with body mass index of 19-30 kg/m2,scheduled for elective TURBT and required ONB before TURBT,were enrolled in the study.ONB was performed with 1.5 ％ lidocaine using the pubic approach under the guidance of a nerve stimulator.The volume of 1.5％ lidocaine was determined by up-and-down sequential trial.The initial volume of hdocaine was 10 ml and the ratio between the two successive volumes was 1.1.Successful ONB was considered to be positive response.The EV50 and 95 ％ confidence interval （CI） of 1.5 ％ lidocaine for ONB were calculated.Results The EV50 of 1.5 ％ lidocaine for ONB was 5.53 rnl and the 95 ％ CI was 5.10-6.00 ml.Conclusion The EV50 of 1.5 ％ lidocaine is 5.53 ml when used for ONB in patients undergoing TURBT.
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2013年第10期1233-1235,共3页
Chinese Journal of Anesthesiology
