摘要
目的:评价五龙颗粒治疗变应性鼻炎肺脾气虚证的改善作用。方法:采用区组随机、双盲单模拟、平行对照、多中心临床研究纳入10家医院585例变应性鼻炎肺脾气虚证患者。共分为3组,试验组351例服用五龙颗粒,对照组117例服用辛芩颗粒及五龙颗粒安慰剂,安慰剂组117例服用五龙颗粒安慰剂。连续服药7天为1个疗程,服药后第4天、第8天复诊1次。观察时间为1个疗程。结果:鼻痒、喷嚏等单项指标计分的变化试验组和对照组均优于安慰剂组,组间差别具有统计学意义。结论:五龙颗粒治疗变应性鼻炎肺脾气虚证具有较好的疗效及安全性。
Objective：To evaluate Wulong Granule in improving allergic rhinitis with Lung and Spleen Qi Deficiency Syndrome. Meth-ods： This is a randomized, double-blind single simulation, parallel-controlled, multi-center clinical study conducted at 10 hospitals, en-rolling 585 patients of allergic rhinitis with Lung and Spleen Qi deficiency syndrome. There are three groups, 351 patients in experimen-tal group took Wulong granule, 117 patients in the positive control group took Xinqin granule and placebo of Wulong granule, 117 pa-tientst in placebo control group took placebo of Wulong granule. The duration of study treatment is 7 days, patient performed clinical vis-it on day 4 and day 8. Results： Individual indicator score of nasal itching, sneezing and other symptoms in positive control group and experimental group were superior to placebo group. A statistically significant difference between them was shown. Conclusion： Wulong granules have good clinical efficacy and safety in treating allergic rhinitis with Lung and Spleen Qi deficiency syndrome.
出处
《世界中医药》
CAS
2013年第11期1298-1299,1302,共3页
World Chinese Medicine
基金
国家科技部重大新药创制项目中药新药临床评价研究技术平台(南京)建设(编号:2012ZX09303009-002)
江苏省人力资源和社会保障厅333高层次人才培养工程及六大人才高峰行动计划
关键词
五龙颗粒
变应性鼻炎
肺脾气虚证
Wulong granule
Allergic Rhinitis
Lung and Spleen Qi Deficiency Syndrome
