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咳嗽变异型哮喘(CVA)应用孟鲁司特钠治疗的临床分析 被引量:2

Clinical analysis of montelukast sodium in the treatment of cough variant asthma(CVA)
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摘要 目的研究分析咳嗽变异型哮喘(CVA)应用孟鲁司特钠(顺尔宁)治疗的临床治疗效果。方法选取我院门诊于2012年5月~2013年5月收治的82例咳嗽变异型哮喘患者,将其随机划分为两组,对照组45例患者单纯接受布地奈德气雾剂治疗,治疗组37例患者接受布地奈德气雾剂及孟鲁司特钠片治疗,对比两组患者治疗前后的哮喘症状缓解时间、治疗前后吸人布地奈德吸人剂量以及哮喘复发率。结果两组患者临床哮喘症状缓解时间、治疗前后吸入布地奈德吸入剂量显著少于对照组,差异有统计学意义(P〈0.05),治疗组哮喘复发率显著低于对照组,对比有统计学意义(P〈0.05)。结论采用孟鲁司特钠治疗咳嗽变异型哮喘,可显著改善患者的肺功能以及临床症状,提高患者生命质量,值得在临床医学中推广使用。 Objective To explore the clinical therapeutic effect of montelukast sodium in the treatment of cough variant asthma (CVA). Methods 82 patients with cough variant asthma(CVA) in our hospital from May 2012 to May 2013 were selected as research objects,and patients were randomly divided into control group(n=45) and treatment group(n=37),the control group received budesonide aerosol solely and the treatment group received bndcsonide aerosol in combination with montelukast sodium tablets,compared the symptom alleviating time, recurrence rate and budesonide inhalation dose before and after treatment between the two groups. Results The symptom alleviating time, recurrence rate and budesonide inhalation dose of treatment group was significantly lower than that of the control group, there was significant difference between the two groups(P 〈 0.05). The recurrence rate of the treatment group was significantly lower than that of the control group, there was significant difference between the two groups(P 〈 0.05). Conclusion Take montelukast sodium for the treatment of cough variant asthma, can significantly improve lung function and clinical symptoms in patients with cough variant asthma,can also improve patient' s life quality, which is worthy of promotion in clinical practice.
作者 姚鹏鲲
出处 《中国医药科学》 2013年第21期84-85,共2页 China Medicine And Pharmacy
关键词 咳嗽变异型哮喘 孟鲁司特钠 布地奈德气雾剂 Cough variant asthma (CVA) Montelukast sodium Budesonide aerosol
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