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降钙素原在老年细菌性肺炎诊断中的临床应用价值 被引量:4

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摘要 目的探讨降钙素原(PCT)在老年细菌性肺炎诊断中的临床应用价值。方法将2007年1月-2012年1月就诊的581例疑似细菌性肺炎老年患者,按出院(或死亡)诊断分为细菌性肺炎组和非细菌性肺炎组,对两组患者在应用抗生素前测定PCT、C反应蛋白(CRP)、外周血白细胞计数(WBC)、中性粒细胞百分比(N%)血沉及痰培养,并比较这些检验指标对细菌性肺炎诊断的灵敏度、特异度、阳性似然比、阴性似然比。结果血清PCT在细菌性肺炎组阳性率高于非细菌性肺炎组。PCT检测对细菌性肺炎诊断的灵敏度为54.45%,特异度为88.46%,阳性似然比为12.69%,阴性似然比为0.17%。CRP灵敏度为95.45%,特异度为8.33%;阳性似然比为4.58%,阴性似然比为3.17%。在各项指标中,PCT的特异度最高,CRP的灵敏度最高,阳性似然比最高为痰培养,阴性似然比最低为PCT。结论血清PCT可作为老年细菌性肺炎的检测指标,其作用优于CRP、WBC、N%、血沉、痰培养等指标;通过与CRP结合,可早期诊断、及时治疗细菌性肺炎。
出处 《华西医学》 CAS 2013年第11期1731-1733,共3页 West China Medical Journal
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