摘要
目的探讨血清降钙素原(PCT)在社区获得性肺炎(CAP)诊断和病情评估中的价值。方法选取2011年5月～2012年5月于本院治疗的72例CAP患者为研究对象,根据CURB-65评分,将所有CAP患者分为轻、中、重症肺炎,并选取健康人群28例为对照组。检测两组血清中PCT浓度,对其相关数据进行统计分析及比较。结果 CAP组治疗后和对照组PCT浓度与治疗前相比较均具有显著性差异(P<0.05);并发症组和无并发症组PCT浓度比较具有显著性差异(P<0.05);重症组PCT浓度与轻症组和中症组相比较,均具有显著性差异(P<0.05);PCT与肺炎严重程度存在相关性,相关系数r=0.620(P<0.05)。结论病情越重的细菌感染肺炎患者,血清PCT浓度越高,PCT水平检测可为CAP的诊断与病情评估提供科学依据。
Objective To evaluate the value of procalcitonin （PCT） in the diagnosis and assessment of community-acquired pneumonia （CAP）. Methods 72 cases with CAP treated in our hospital from May 2011 to May 2012 were selected as research object. According to CURB-65 score, the patients were divided into mild pneumonia, moderate pneumonia and severe pneumonia. 28 healthy people were selected as control group. The concentration of PCT was detected in serum of two groups, the related data was statistically analyzed and compared. Results The concentration of PCT after treatment of CAP group and the control group had significant difference with the concentration of PCT before treatment of CAP group （P＆lt;0.05）. There was significant difference in the concentration of PCT between complication group and non-complication group. The concentration of PCT of severe pneumonia group had significant difference with mild pneumonia group and moderate pneumonia group. There was a strong correlation between the concentration of PCT and severity of pneumonia, r=0.620 （P＆lt;0.05）. Conclusion The illness is more serious in pneumonia patients of bacterial infection, the higher the concentration of serum PCT. PCT level detection can provide a scientific basis for the diagnosis and assessment of CAP.
出处
《中国现代医药杂志》
2013年第6期42-44,共3页
Modern Medicine Journal of China
