摘要
目的分析脑胶质瘤患者的存活、预后影响因素。方法对该院2001～2010年收治的133例脑胶质瘤患者进行回顾性分析，选择患者的性别、年龄、手术前的KPS评分、病理分级、肿瘤长径、手术是否完全切除肿瘤、是否行术后放射治疗等因素进行单因素和多因素分析。结果全组患者中位随访时间36个月，随访率为93％，随访满3年者73例，1、2、3年生存率分别为93％、82％、70％，中位生存时间为62．7个月。多因素回归分析显示病理分级、肿瘤长径、是否行术后放射治疗对生存率有影响。结论高病理分级、肿瘤长径大于或等于6cm的脑胶质瘤预后不良，手术治疗联合术后放射治疗可以提高脑胶质瘤的远期生存率。
Objective To explore the prognosis and related factors of brain glioma. Methods 133 patients who have been con firmed pathology with brain glioma from Jan. 2001 to Dec. 2010 were retrospectively analyzed. The factors such as sex, age, func- tional status,histological character,the longest diameter of tumor,surgical excision of part or all of the tumor,whether or not being radiotherapy after surgical excision were selected to evaluate by single factor and multiple factors analysis. Results The median fol low-up time was 36 months,The follow-up rate was 930//00.73 cases were followed up for 3 years,the 1-- ,2-- and 3-- year survival rate was 93 ~, 82 ~//0 and 70 ~, respectively, the median survival time was 62.7 months. Multiple factors regression analysis showed that histological character, the longest diameter of tumor and whether or not being radiotherapy after surgical excision were related to prognosis. Conclusion High-grade of histological character,the longest diameter of tumor≥6 cm predict poor prognosis, postop- erative radiotherapy can improve the survival of glioma.
出处
《重庆医学》
CAS
CSCD
北大核心
2013年第32期3908-3910,共3页
Chongqing medicine
关键词
脑胶质瘤
术后放疗
预后因素
glioma
postoperative radiotherapy ~ prognostic factors
