摘要
目的:探讨血浆同型半胱氨酸(Hcy)水平与慢性重度心力衰竭患者预后的关系。方法:抽取85例慢性重度心力衰竭患者外周静脉血,检测其血浆Hcy水平,回顾性分析上述患者各项临床资料,并分析血浆Hcy水平与患者预后的相关性。结果:慢性重度心衰患者平均血浆Hcy水平为(17.6±4.9)μmol/L,明显高于正常人群;死亡组慢性重度心衰患者平均年龄大于存活组,其高血压和糖尿病的罹患率明显高于存活组患者,差异具有统计学意义(P<0.05);死亡组患者血浆Hcy水平明显高于存活组,差异具有统计学意义(P<0.05)。结论:慢性心力衰竭患者年龄、既往患有高血压、糖尿病,以及其血浆Hcy水平是慢性重度心力衰竭患者发生死亡的独立预测因素。
Objective：To explore the relationship of plasma homocysteine（Hcy）levels and prognosis of patients with severe chronic heart failure. Method：The peripheral blood from 85 cases patients with severe chronic heart failure was extracted which was used to detect plasma Hcy levels.The clinical data of all patients were retrospectively analyzed,the relationship of its with Hcy levels. Result：The mean of plasma Hcy level from patients with severe chronic heart failure was（17.6 ± 4.9）umol/L,significantly higher than the normal population;Severe chronic heart failure death group average age of patients is greater than the survival group,the prevalence of hypertension and diabetes was significantly higher than the survival of patients,the difference was statistically significant（P〈0.05）;death in patients plasma Hcy levels were significantly higher than the survival group patients,the difference was statistically significant（P〈0.05）. Conclusion：The age of patients with chronic heart failure,history of hypertension,diabetes,and their plasma Hcy levels in patients with severe chronic heart failure are independent predictors of mortality.
出处
《中国医学创新》
CAS
2013年第32期141-142,共2页
Medical Innovation of China
