摘要
【目的】探讨血清尿酸（SUA）水平与代谢综合征（MS）各组分的关系，探讨SUA水平对冠心病发生的预测价值。【方法】回顾性分析了400例因胸痛接受冠状动脉造影检查的患者，按照SUA水平（≤280、281～339、340399、≥400μmol／L）分为4个分位组，观察入选患者sUA水平与MS各组分之间的关系。并依据冠心病确诊情况分为冠心病组（280例）和非冠心病组（120例），分析sUA水平与冠心病发生是否存在相关性。【结果】SUA水平升高与性别、年龄、高血压、体质量指数、高甘油三脂血症密切相关（P＜0．01）。冠心病组SUA水平显著高于非冠心病组（P＜0．01）。Logistic回归分析显示，SUA水平升高仍是本组冠心痛发病的独立危险因素之一。【结论】高尿酸血症与MS各组分具有密切的联系，是冠心病发病独立危险因素。
[Obiective]To explore the relationship of serum uric acid（SUA） level with the components of metabolic syndrome（MS） and coronary heart disease（CHD）. [Methods] Totally 400 patients who received coronary angiography be＇cause of chest pain. were analyzed retrospectively. According to SUA level（≤280, 281 -339, 340-399, ≥400μmol/L）, all patients were divided into 4 groups. The relationship between SUA level and the components of MS in patients was observed. According to the diagnosis of CHD, patients were divided into CHD group（ n =280） and non-CHD group（ n = 120）. The correlation between SUA level and the occurrence of CHD was analyzed. [Results]The increasing of SUA level was closely correlated with gender, age, hypertension, body mass index and hyperlipemia（ P 〈0.01）. The SUA level in CHD group was signifieantly higher than that in non-CHD group（ P 〈0.01）. Logistic regression analysis revealed that the increasing of SUA level was still one of independent risk factors of CHD in the group. [Conclusion]Hyperlipemia is closely related with the components o{ MS, and it is a independent risk factor for the incidence of CHD.
出处
《医学临床研究》
CAS
2013年第10期2003-2005,共3页
Journal of Clinical Research
关键词
代谢综合征X
冠心病
尿酸
血液
Metabolic Syndrome X
Coronary Disease
Uric Acid/BD
