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高危型人乳头瘤病毒DNA载量与子宫颈上皮内瘤变关系的探讨 被引量：1

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摘要 目的探讨高危型人乳头瘤病毒(HR-HPV)感染与宫颈上皮内瘤变(CIN)的关系。方法采用第二代杂交捕获方法 (HC2)和宫颈液基细胞学检测1 500例妇女HR-HPVDNA和宫颈细胞学,对有指征的妇女行阴道镜下活检。比较不同病变患者中高危型HR-HPV的感染率,分析病毒负荷量与CIN的关系。结果 CIN1、CIN2和CIN3中HR-HPV感染率分别为58.57%(41/70)、87.50%(42/48)、93.30%(24/26),三者比较,差异有统计学意义(P<0.05)。CIN1患者HR-HPV载量低于CIN2和CIN3(P<0.05),但CIN2、CIN3患者HR-HPV病毒载量比较,差异无统计学意义(P>0.05)。结论 HR-HPV感染率随CIN病变程度的加重而增加,较高的的HR-HPV病毒载量与高度CIN密切相关。
作者 蔡和伶 彭晓琴
机构地区 重庆市万州区妇幼保健院妇科
出处 《中国妇产科临床杂志》 2013年第6期542-543,共2页 Chinese Journal of Clinical Obstetrics and Gynecology
关键词 人乳头瘤病毒 子宫颈上皮内瘤变 病毒载量
分类号 R737.33 [医药卫生—肿瘤]
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共引文献80

同被引文献14

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中国妇产科临床杂志
2013年 第6期

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