摘要
目的:探讨神经电生理检测对格林-巴利综合征(GBS)的诊断价值。方法:回顾性分析18例GBS患者的神经电生理资料:运动神经传导速度(MCV)、感觉神经传导速度(SCV)、F波、H反射、针电极肌电图。结果:①18例GBS患者的MCV异常率为76.87%,SCV异常率为39.62%,上肢NCV异常率为58.57%,下肢NCV异常率为63.00%。MCV异常率明显高于SCV,而上肢和下肢NCV的异常率的差异无统计学意义。②F波异常率77.94%,H反射异常率69.44%。F波与NCV异常率的差异有统计学意义,F波与H反射异常率的差异有统计学意义。③18例GBS患者中,4例单纯可见自发电位,4例表现为神经源性损害。针电极肌电图异常率41.67%。结论:GBS患者运动神经纤维损害较感觉神经纤维损害重;F波为GBS早期诊断的敏感指标;GBS患者针电极肌电图检测表现为神经源性损害;NCV、F波、H反射及针电极肌电图相结合可明显提高GBS检出率。
Objective： To investi gate the significance of nerve electrophysiology in patients with Guillain-Barre Syndrome （ GBS ）. Methods：Electrophysiologieal data were retrospectively analyzed in 18 patients with GBS ,which included motor conduction velocity（MCV）, sensory conduction velocity （SCV）, F wave,H reflex and electromyography （EMG）. Results： ①The abnormal rate of MCV was 76.87% and that of SCV was 39.62%. The abnormal rate of NCV in upper limbs was 58.57%, and the abnormal rate of NCV in lower limbs was 63.00%. There was significant difference of MCV and SCV of 18 cases with GBS. There was no significant difference of the upper limbs and the lower limbs in NCV. ②The abnormal rate of F wave Was 77.94% and that of H reflex was 69.44%. There are significant difference of F and NCV of 18 cases with GBS. There was significant difference of F and H of 18 cases with GBS. ③The abnormal rate of EMG was 41.67%.In the 18 cases with GBS,there were 4 patients with the positive sharp waves and fibrillation potential of EMG,and 9 patients with the neurogenic damage of EMG. Conclusion： The injury of distal motor nerve is more severe than that of sensory nerve and the F wave are sensitive indices for the early diagnosis of GBS. EMG reveals the neurogenie damage,F wave can not substitute conventional nerve electrophysiology methods in which the diagnostic sensitivity earl be improved if all the parameters are used together.
出处
《甘肃医药》
2013年第10期734-737,共4页
Gansu Medical Journal
关键词
格林-巴利综合征
神经电生理
GuiUain-Barre Syndrome
nerve electrophysiology
