摘要
目的研究变应性鼻炎患者发病的相关因素及发病特征,调查变应性鼻炎患者中医证型及临床症状特点。方法收集846例变应性鼻炎患者(变应性鼻炎组)完整临床资料,以同期212例慢性鼻炎患者作为对照组,对发病相关因素进行单因素分析和多因素非条件Logistic回归分析,总结分析患者临床特点及中医临床证型。结果性别分布差异无统计学意义(P>0.05),年龄分布以青年占比最高,并随年龄增长而递减,各年龄段构成比差异有统计学意义(P<0.05)。变应性鼻炎组有既往其他变应性疾病史、目前伴发其他变应性疾病、家族过敏史、直系亲属变应性鼻炎史、居住或工作场所接触粉尘、近3年居住或工作场所装修、吸烟或二手烟、居住或工作场所通风不好、变迁生活地的患者占比显著高于对照组(P<0.05)。既往其他变应性疾病史、近3年居住或工作场所装修、变迁生活地、直系亲属变应性鼻炎史是变应性鼻炎发生的主要危险因素(P<0.05),居住或工作场所通风好是变应性鼻炎发生的保护因素(P<0.05)。发病诱因主要为温度变化,发作主要季节为春季和秋季。主要中医临床证型为肺气虚弱、脾气虚弱,肾阳不足、肺经伏热证相对较少,肺气虚弱证的患者主要呈间歇性发作且症状较轻,脾气虚弱、肾阳不足、肺经伏热证患者以持续发作为主且症状较重。结论变应性鼻炎发病与体质、环境、遗传等因素密切相关,温度变化、春季和秋季分别是主要的发病诱因和发作季节,中医临床证型以虚证为主,肺气虚弱最常见。
Objective To study the related pathogenic factors and clinical characteristics of patients with allergic rhinitis, and investigate their TCM syndrome types and features of clinical symptoms. Methods The clinical features and TCM clinical syndrome types of patients with allergic rhinitis were summarized and analyzed by collecting complete clinical data of 846 pa- tients with allergic rhinitis （allergic rhinitis group）, then 212 patients with chronic rhinitis during the same period were chosen as control group, and the related pathogenic factors were analyzed by single factor analysis and muhifactor unconditioned Lo- gistic regression analysis. Results The differences in gender distributions had no statistical significances （P 〉 0.05）; the age distributions had the highest proportion in youth and decreased with age, the differences among constituent ratios of all ages had statistical significance （P 〈 0.05）. In allergic rhinitis group, the proportion of patients who had a history of other allergic diseases, currently combined with other comorbid allergic diseases, family history of allergies, immediate family history of allergic rhinitis, dust exposure in living or work place, decoration of living or work place in recent 3 years, smoking or second- hand smoke, poor ventilation in living or work place, and changes of living place were significantly higher than those in control group （P 〈 0.05）. History of other previous allergic diseases, decoration of living or work place in recent 3 years, changes of living place, and immediate family history of allergic rhinitis were major risk factors of allergic rhinitis occurrence （P 〈 0.05）; good ventilation in living or work place was protecting factor of allergic rhinitis occurrence （P 〈 0.05）. Temperature change was the major predisposing factor, and the main season of attack was spring and autumn. Main TCM clinical syndrome types included weakness of lung-qi and kidney-qi, while deficiency of kidney-yang and lung meridian latent pyrexia s
出处
《中国医药导报》
CAS
2013年第31期125-128,共4页
China Medical Herald
关键词
鼻炎
变应性
危险因素
辨证分型
Rhinitis
Allergic
Risk factors
Syndrome differentiation
