摘要
目的对比研究超薄瓣准分子激光原位角膜磨镶术（laser in situ keratomileusis，LASIK）与准分子激光上皮瓣下角膜磨镶术（laser epithelial keratomileusis，LASEK）治疗薄角膜高度近视患者的疗效。方法选择近视度数〉-6．00D且角膜中央厚度450—500μm的患者43例（79眼），随机分为两组，A组患者22例（41眼）接受超薄瓣LASIK治疗，B组患者21例（38眼）接受LASEK治疗。观察两组患者术后角膜厚度、视力情况，同时观察患者术后屈光度和haze情况。结果两组患者均手术成功，A组患者术后无明显不适及不良反应，效果满意。B组患者术后多有不适主诉，尤以术后1d和摘除角膜接触镜后1d最为明显，术后无明显不良反应。A组患者术后1个月时视力≥1．O的患者比例（63．41％）较B组（39．47％）高，差异有统计学意义（P〈0．05），而术后3个月、6个月、12个月两组视力差异均无统计学意义（均为P〉0．05）。两组患者术后各时间点屈光度与术前比较，差异均有统计学意义（均为P〈0．05）；A组患者术后3个月、6个月、12个月屈光度均显著高于B组，差异均有统计学意义（均为P〈0．05）。A组患者术后无haze发生，而B组术后不同时间均有一定程度的haze发生。结论超薄瓣LASIK较LASEK术后稳定性好．患者预后曼好．
Objective To evaluate the efficacy of super-thin flap laser in situ keratomileusis（LASIK） and laser epithelial keratomileusis （LASEK） on correcting high myopia with relative thin cornea. Methods A taotal of 43 patients （49 eyes） under- went super-thin flap LASIK or LASEK surgery for correcting high myopia（ 〉 -6.00 D） with relative thin cornea（ central corneal thickness 〈 500 μm） ,including 22 patients（41 eyes） for LASIK（group A） and 21 patients（38 eyes） for LASEK（group B）. The corneal thickness, visual acuity, remained diopter and corneal haze of the patients in two groups were examined after operation. Results All surgeries were successful. Patients in group A had no obvious complication, the satisfaction was high. Patients in group B had different degree of uncomfortable feeling, especially at postoperative 1 day and 1 day afat postoperative 1 month in group A was more than that in group B ,there was statistical difference（P 〈 0.05 ） ,but there was no statistical difference at postoperative 3 months, 5 months and 12 months （all P 〉 0.05 ）. Compared with pre-operation, there were statistical differences in diopter at postopertive time points of two groups （ all P 〈 0.05 ）, and the postoperative diopter at 3 months,5 months and 12 months in group A were significant higher than that in group B, there were statistical differences（ all P 〈 0.05 ）. No haze apperaed in patients of group A,but certain degree of haze occurred in group B after operation. Conclusion Super-thin flap LASIK has more postoperative stablity and well prognosis than LASEK.
出处
《眼科新进展》
CAS
北大核心
2013年第11期1068-1069,1072,共3页
Recent Advances in Ophthalmology
