摘要
目的研究安步乐克(盐酸沙格雷酯片)对缺血性脑卒中患者血清炎性标志物的影响。方法选择40例缺血性脑卒中患者,随机平均分为2组。2组均给予相同的基础药物治疗,同时分别给予安步乐克(治疗组)和阿司匹林(对照组)治疗。观察2组治疗后临床疗效和血清炎性因子的变化。结果用药2周后,2组神经功能缺损评分较治疗前显著降低,差异有统计学意义(P<0.05);同时治疗组比对照组降低显著,差异有统计学意义(P<0.05)。治疗2周后2组炎性因子水平均较治疗前显著下降,差异有统计学意义(P<0.05);治疗组明显低于对照组,差异有统计学意义(P<0.05)。结论安步乐克治疗缺血性脑卒中效果明显,其作用可能与降低炎性因子水平有关。
Objective To explore the effect of anplag （ sarpogrelate hydreehloride tablets） on senma inflammatory markers of patients with iachemie stroke. Methods 40 cases of patients were randomly divided into treatment group and con- trol group. Both groups were given the same basic drugs for treatment, while the treatment group was given anplag and the con- trol group was given aspirin for treatment. The clinical effect and changes of serum inflammatory factors of 2 groups were ob- served. Results After 2 weeks for treatment,the neurologic impairment score of 2 groups significantly decreased,and the difference was statistically significant （P 〈0.05） ;the neurologic impairment score of treatment groups decreased significantly compared with the control group,and the difference was statistically significant （P 〈0.05）. After 2 weeks for treatment,the levels of inflammatory factors of 2 groups significantly decreased,and the difference was statistically significant （P 〈0.05 ） ;the levels of inflammatory factors of treatment group was lower than that of the control group,and the difference was statistically sig- nifinant （P 〈 0.05）. Conclusion The effect of anplag is definite in the treatment of isehemic stroke, this may be related to reducing the inflammatory factor levels.
出处
《临床合理用药杂志》
2013年第29期3-4,共2页
Chinese Journal of Clinical Rational Drug Use
