摘要
目的 探讨醒脑静注射液对急性缺血性脑卒中患者的临床疗效及其对炎症因子的影响.方法 选取枣庄市立医院收治的140例急性缺血性脑卒中患者的临床资料,将所有患者随机分为观察组（常规治疗＋醒脑静）70例和对照组（常规治疗）70例,观察两组患者的临床疗效、白细胞介素-6等炎症因子的变化以及NIHSS评分情况.结果 经过1个疗程的治疗,观察组总有效率优于对照组,差异有统计学意义（P＜0.05）；两组患者经过治疗后,C-反应蛋白、肿瘤坏死因子-α及白细胞介素-6较治疗前显著好转,且组间比较差异有统计学意义（P＜0.05）；两组患者治疗后NIHSS评分情况较治疗前有显著下降,差异有统计学意义（P＜0.05）.结论 急性缺血性脑卒中在常规治疗基础上加用醒脑静注射液,可以有效的提高临床疗效,抑制患者的炎症反应,促使患者神经功能缺损指标的恢复等,值得临床推荐.
Objective To investigate the clinical efficacy of Xingnaojing injection on acute ischemic stroke and it＇ s effects on inflammatory factors.Methods One hundred and forty patients with acute ischemic stroke were randomly divided into two groups,including observation group （70 cases with conventional and Xingnaojing treatment） and the control group （70 patients with conventional treatment）.The clinical efficacy,changes of inflammatory factors and NIHSS scores were compared between the two groups.Results After a course of treatment,the total efficiency in the observation group was better than that in the control group（P ＜0.05） ; the indicators such as CRP,TNF-α,IL-6 in the observation group were better than those in the control group （P ＜ 0.05） ; and the NIHSS score in the observation group was better than that in the control group（P ＜ 0.05）.Conclusions Conventional treatment combined with Xingnaojing injection in the treatment of acute ischemic stroke can effectively improve the clinical efficacy,promote recovery of neurologic impairment indicators,and it＇ s worth to be clinically recommended.
出处
《中国实用医刊》
2013年第21期64-65,共2页
Chinese Journal of Practical Medicine
