摘要
对比剂肾病是院内获得性急性肾功能衰竭主要原因之一,发病率一般在3.3%~8%,在慢性肾功能不全或糖尿病患者中发病率可能更高.确切的发病机制尚不清楚,可能包括肾缺血及对比剂的直接毒性作用,目前尚无特异的治疗方法,预防措施包括：水化、药物、血透.
Contrast-induced nephropathy is the leading cause of hospital-acquired acute kidney injury. The incidence ranges from 3.3% to 8% and higher in patient with chronic kidney disease or diabetes mellitus. The exactly pathogenesis of contrast-induced nephropathy is unknown, but it may be involved renal ischemia from various mediators and direct tubular injury from reactive oxygen species. Currently, there is no effective treatment. Many prophylactic regimens include hydration, medications and hemodialysis.
出处
《心血管病学进展》
CAS
2013年第5期658-660,共3页
Advances in Cardiovascular Diseases
关键词
对比剂肾病
发病机制
危险因素
预防
contrast-induced nephropathy
pathogenesis
risk factors
prevention
