期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

早期强化阿托伐他汀治疗对ACS患者PCI术后血清hs-CRP、NT-proBNP和sCD_(40)L水平的影响 被引量：4

下载PDF
导出
摘要 目的探讨早期强化阿托伐他汀治疗对急性冠脉综合征(ACS)患者PCI术后血清超敏C反应蛋白(hsCRP)、N末端B型脑钠肽(NT-proBNP)和可溶性CD40配体(sCD40L)的影响。方法 80例行PCI手术的ACS患者随机分为观察组和对照组,各40例。观察组患者在PCI术前和术后1个月均采用阿托伐他汀40 mg/d治疗,1个月后改为维持剂量20 mg/d;对照组仅采用阿托伐他汀20 mg/d治疗。术前、术后1、3个月测定所有患者血清hsCRP、NT-proBNP和sCD40L水平。结果两组均顺利完成PCI治疗。与治疗前相比,两组治疗后1、3个月血清hsCRP、NT-proBNP和sCD40L水平均降低(P<0.05或<0.01)。与对照组术后1、3个月时相比,观察组患者血清hsCRP、NT-proBNP和sCD40L水平均降低(P<0.05或<0.01)。结论早期强化阿托伐他汀治疗可降低ACS患者PCI术后血清hs-CRP、NT-proBNP和sCD40L水平。
作者 张奇志 魏明芬 王蒙
机构地区 山东省交通医院
出处 《山东医药》 CAS 2013年第35期44-46,共3页 Shandong Medical Journal
关键词 阿托伐他汀 强化 超敏C反应蛋白 N末端B型脑钠肽 可溶性CD40配体
分类号 R543.3 [医药卫生—心血管疾病]
  • 相关文献

参考文献14

  • 1Cannon CP,Braunwald E,McCabe CH,et al.Intensive versus moderate lipid lowering with statins after acute coronary syndromes[J].N Engl J Med,2004,350(15):1495-1504. 被引量：1
  • 2Tan J,Hua Q.Correlations between serum inflammation factors and left ventricular remodeling in acute ST segment elevation myocardial infarction[J].Yonsei Med J,2012,53(3):501-507. 被引量：1
  • 3Frasure-Smith N,Lespérance F,Irwin MR,et al.Depression,Creactive protein and two-year major adverse cardiac events in men after acute coronary syndromes[J].Biol Psychiatry,2007,62(4):302-308. 被引量：1
  • 4Mach F,Sch(o)nbeck U,Fabunmi RP,et al.T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD4o L-dependent mechanism:implications for tubule formation[J].Am J Pathol,1999,154(1):229-238. 被引量：1
  • 5Türker S,Güneri S,Akdeniz B,et al.Usefulness of preprocedural soluble CD4o ligand for predicting restenosis after percutaneous coronary intervention in patients with stable coronary artery disease[J].Am J Cardiol,2006,97(2):198-202. 被引量：1
  • 6Eren NK,Ertas F,Yüksek U,et al.Additive prognostic value of NT-proBNP over TIMI risk score in intermediate-risk patients with acute coronary syndrome[J].Turk Kardiyol Dern Ars,2009,37(1):1-8. 被引量：1
  • 7Yang YJ,Zhao JL,You SJ,et al.Post-infarction treatment with simvastatin reduces myocardial no-reflow by opening of the KATP channel[J].Eur J Heart Fail,2007,9(1):30-36. 被引量：1
  • 8Nicholls SJ,Brandrup-Wognsen G,Palmer M,et al.Meta-analysis of comparative efficacy of increasing dose of Atorvastatin versus Rosuvastatin versus Simvastatin on lowering levels of atherogenic lipids (from VOYAGER)[J].Am J Cardiol,2010,105(1):69-76. 被引量：1
  • 9Patti G,Pasceri V,Colonna G,et al.Atorvastatin pretreatment improves outcomes in patients with acute coronary syndromes undergoing early percutaneous coronary intervention:results of the ARMYDA-ACS randomized trial[J].J Am Coll Cardiol,2007,49(12):1272-1278. 被引量：1
  • 10Rodés-Cabau J,Tardif JC,Cossette M,et al.Acute effects of sta tin therapy on coronary atherosclerosis following an acute coronary syndrome[J].Am J Cardiol,2009,104(6):750-757. 被引量：1

二级参考文献30

  • 1林毅,陈新民,罗助荣,盖晓波.不同剂量阿托伐他汀对急性冠脉综合征患者体内炎症反应、血小板活性及纤溶活性的影响[J].医学信息（西安上半月）,2007,20(6):973-976. 被引量：18
  • 2[1]DE LEMOS J A,MORROW D A,BENTLEY J H,et al.The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes[J].N Engl J Med,2001,345 (14):1014-1021. 被引量：1
  • 3[2]OMLAND T,PERSSON A,NG L,et al.N-terminal pro-B-type natriuretic peptide and long-term mortality in acute coronary syndrome[J].Circulation,2002,106(23):2913-2925. 被引量：1
  • 4[3]HAMMERER-LERCHER A,NEUBAUER E,MULLER S,et al.Head-to-head comparison of N-terminal pro-brain natriuretic peptide,brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction[J].Clin Chim Acta,2001,310(2):193-197. 被引量：1
  • 5[4]HAMA N,ITOH H,SHINABAMI G,et al.Rapid ventricular induction of brain natriuretic peptide gene expressions in experimental acute myocardial infarction[J].Circulation[J],1995,92 (6):1558-1564. 被引量：1
  • 6[5]SADANANDAN S,CANNON C P,CHEKURI K,et al.Association of elevated b-type natriuretic peptide levels with angiographic findings among patients with unstable angina and non-ST segment elevation myocardial infarction[J].J Am Coll Cardiol,2004,44(3):564-568. 被引量：1
  • 7林毅,罗助荣,盖晓波.不同剂量阿托伐他汀对2型糖尿病患者体内炎症的影响[J].心血管康复医学杂志,2007,16(4):380-382. 被引量：10
  • 8Ross R. Atherosclerosis: an inflammatory disease [ J ]. N Engl J Med,1999,340(2) :115 -126. 被引量：1
  • 9Hanley JA,Mcnril BJ. The meaning and use of the area under a ROC curve[ J]. Radiology,1982,143:29 -36. 被引量：1
  • 10Noelle RJ. CD40 and its ligand in host defense [ J ]. Immunity, 1996,4:415 -419. 被引量：1

共引文献27

同被引文献40

  • 1任更朴,房忠卫,刘淑会,王扬.PCI围手术期联合检测血清NT-PROBNP和cTn在老年急性冠脉综合征中的应用[J].中国生化药物杂志,2014,34(4):84-87. 被引量：14
  • 2高学忠,马建军,阿米娜.马木提.急性冠脉综合征患者PCI术后抑郁症危险因素分析[J].山东医药,2013,53(30):33-34. 被引量：6
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33004
  • 4Beer C, Blacker D, Byneveh M, et al. A randomized placebo con- trolled trial of early treatment of acute ischemic stroke with atorvas- tatin and irbesartan[J]. Int J Stroke, 2012,7(2) :104-111. 被引量：1
  • 5Mokin M, Darkhabani Z, Binning MJ, et al. Small unruptared partial- ly thrombosed aneurysms and stroke: report of three cases and review of the literature[J]. J Neurointerv Surg, 2012,4(3):e6. 被引量：1
  • 6Guan W, Kozak A, Fagan SC. Drug repurposing for vascular pro- tection after acute ischemic stroke [ J ]. Acta Neurochir Suppl, 2011, ( 111 ) :295-298. 被引量：1
  • 7Zhang X, Deguchi S, Deguchi K, et al. Amlodipine and atorvasta- tin exert protective and additive effects via antiapoptotic and antiau- tophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats [ J ]. J Neurosci Res, 2011,89 (8) :1228-1234. 被引量：1
  • 8Muscari A, Puddu GM, Santoro N, et al. The atorvastatin during ischemic stroke study: a pilot randomized controlled trial[J]. Clin Neuropharmacol, 2011,34 (4) : 141-147. 被引量：1
  • 9Ming-Shian Tsai,Yu-Fen Li,Cheng-Li Lin,Yao-Chun Hsu,Po-Huang Lee,Fung-Chang Sung,Chia-Hung Kao.Long-term risk of acute coronary syndrome in patients with cholangitis: A 13-year nationwide cohort study[J].European Journal of Internal Medicine.2014(5) 被引量：1
  • 10Nicole K. Gillis,Cynthia Arslanian-Engoren,Laura M. Struble.Acute Coronary Syndromes in Older Adults: A Review of Literature[J].Journal of Emergency Nursing.2014(3) 被引量：1

二级引证文献32

山东医药
2013年 第35期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部