摘要
以蒎酮酸为原料,经酰氯化、亲核取代、亲核加成等反应,与取代苯胺生成了7个含四元环结构的酰基硫脲衍生物,其中6个为首次合成。所合成的产品经IR、1HNMR进行了结构鉴定。研究了所合成化合物对亚洲玉米螟的杀虫活性,该类化合物对亚洲玉米螟表现出一定的杀虫活性,并表现出一定的构效关系。
Seven acylthioureas derivatives containing a cy- clobuane ring were synthesized via acylchlorination, nucleo- philic substitution and nucleophiIic addition reaction using pi- nonic acid and substituted aniline as raw materials and six of which were obtained firstly. The structures were confirmed by IR and 1HNMR. The insecticidal activity of the synthetic de- rivatives against Ostrinia furnacalis was invesitigated. The re- suits indicated that synthetic derivatives showed certain insec- ticidal activity against Ostrinia furnacalis. Moreover a close relationship between their structure and effect was estab- lished.
出处
《化学试剂》
CAS
CSCD
北大核心
2013年第10期929-932,共4页
Chemical Reagents
基金
国家质检总局科技计划资助项目(2012QK242)
山东省质监局科研资助项目(2012KYZ32)
关键词
酰基硫脲
蒎酮酸
杀虫活性
acylthiourea
pinonic acid
insecticidal activity
