摘要
目的探讨急性脑梗死患者血清超敏C反应蛋白（hsCRP）、氧化低密度脂蛋白（ox-LDL）及同型半胱氨酸（Hcy）水平的相关性。方法选择我院2006年12月至2011年12月间住院诊治的急性脑梗死患者90例,根据患者入院后24 h内的神经功能缺损程度评分,将患者分为轻度神经功能缺损（〈4分）32例,中度神经功能缺损（4~15分）45例,重度神经功能缺损（〉15分）13例。测定并分析三组的hsCRP、ox-LDL及Hcy水平。结果神经功能缺损轻度、中度和重度患者在hsCRP、oxLDL及Hcy三个指标上均存在不同程度的差异,而且随着患者病情的加重,hsCRP、ox-LDL及Hcy水平三者均出现增高趋势,且轻度型、中度和重度型三种情况下的hsCRP、ox-LDL及Hcy水平均出现显著差异（P〈0.05）。结论 hsCRP、ox-LDL及Hcy水平三个指标对于急性脑梗死的检测具有重要的临床诊断价值。
Objective To investigate the relationships among serum high-sensitive C-reactive protein（hsCRP）,oxidized low-density lipoprotein（ox-LDL） and homocysteine（Hcy） levels in patients with acute cerebral infarction.Methods 90 patients with acute cerebral infarction in our hospital from December 2006 to December 2011 were divided into 3 groups according to the neurological deficiency score within 24 hours after admission： 32 cases of mild neurological deficiency（4）,moderate neurological deficiency（4 ~ 15） and severe neurological deficiency（15）.The hsCRP,ox-LDL and Hcy levels of 3 groups were detected.Results There were significant differences of hsCRP,ox-LDL and Hcy levels among 3 groups,and with the deterioration of the patients＇ condition,hsCRP,ox-LDL and Hcy levels showed the tendency of increase,the differences of hsCRP,ox-LDL and Hcy levels among 3 groups were statistically significant（P 0.05）.Conclusions The hsCRP,ox-LDL and Hcy levels have important clinical diagnostic value for acute cerebral infarction.
出处
《临床医学工程》
2013年第9期1129-1130,共2页
Clinical Medicine & Engineering
关键词
急性脑梗死
超敏C反应蛋白
氧化低密度脂蛋白
同型半胱氨酸
Acute cerebral infarction
High-sensitive C-reactive protein（hsCRP）
Oxidized low-density lipoprotein（ox-LDL）
Homocysteine（Hcy）
