摘要
卵泡膜细胞在卵泡的发生和发育过程中起了至关重要的作用,在卵泡相关研究中,人们更多的关注颗粒细胞而忽略了膜细胞。研究表明,卵泡膜细胞可为卵泡发育提供所必需的雄激素;参与形成血管系统并为卵泡发育提供营养物质和性激素;介导卵母细胞与颗粒细胞之间的交互作用进而参与调控细胞凋亡和卵泡发育过程。因此,本文就哺乳动物卵巢卵泡膜细胞功能的研究现状进行综述,旨在引起人们对卵泡膜细胞功能研究的关注,并为卵泡膜细胞的深入研究提供参考。
Over the past decade, researches on follicular biology are focused on granulosa cells and their interaction with the oocyte. While, the theca cell has been somewhat forgotten as a necessa- ry and vital part of the folliculogenesis and follicular developmental process in the mammalian ovary. Theca cells synthesize androgens required by the developing follicles, modulate angiogene- sis and provide essential nutrients and steroid hormones along follicular developmental process. Their function is also enabled to contribute the process of cell apoptosis and follicular develop- ment via mediating the crosstalk with oocyte and granulosa cells. In this study, the advance in the function of theca cells in the mammalian ovary are reviewed to represent the crucial role of theca cells during follicular development and promote the research on the function of theca cells.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
2013年第9期1337-1341,共5页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
国家自然科学基金资助项目(31201798)
高等学校博士学科点专项科研基金项目资助(20105103120003)
