摘要
镰刀菌毒素是指镰刀菌属的毒性代谢产物,其中单端孢霉烯族毒素是粮食中最常见的一类污染性镰刀菌毒素,可以引起人或动物急性、慢性毒性作用,部分霉菌毒素已证明具有致突变性及致癌性。流行病学及体内、体外实验研究结果表明,部分镰刀菌毒素对人或动物生殖细胞、受孕、妊娠、分娩、哺乳等亲代生殖机能以及对其子代胚胎-胎儿发育、出生后发育产生不良影响。本文对镰刀菌毒素生殖、发育毒性研究及其进展进行综述。
Fusarium toxins,the metabolites of trichothecenes,zearalenone and fumonisins,are widespread in cereals and their products which can cause toxic effects through oral chronic exposure to human and animals.Fusarium toxins also have specific toxic effects,such as metabolism disorders,liver toxicity,kidney toxicity,neurotoxicity,skin phototoxicity,hematopoietic toxicity and so on.Mycotoxins have been shown to have mutagenic and carcinogenic effects and some fusarium toxins can cause reproductive and developmental toxicities to human and animals.This paper reviews the reproductive and developmental toxicity of fusarium toxins on human and animal.
出处
《中国食品卫生杂志》
北大核心
2013年第5期474-478,共5页
Chinese Journal of Food Hygiene
基金
国家科技重大专项资助项目(2009ZX09501-034)
关键词
镰刀菌毒素
生殖毒性
发育毒性
食品污染物
Fusarium toxin
reproductive toxicity
developmental toxicity
food contaminant
