摘要
目的探讨引起妇产科患者多药耐药菌感染的高危因素,为制定多药耐药菌感染的干预措施提供参考。方法选取新疆维吾尔自治区人民医院北院妇产科2010-2013年收治的132例患者,所有患者均行创面细菌培养及药敏试验,将其中31例多药耐药菌感染患者设为试验组,101例患者设为对照组,对比分析两组患者的年龄大小、住院时间、术后白蛋白、白细胞数、血红蛋白、使用抗菌药物数量及时间等。结果 132例患者中有31例多药耐药菌感染,感染率为23.5%,检出多药耐药菌以金黄色葡萄球菌、大肠埃希菌为主,分别占41.9%、25.8%;多药耐药菌感染与抗菌药物使用种类、抗菌药物使用时间、术后白蛋白量及术后白细胞数均有显著关系(P<0.05);多因素回归分析显示多种抗菌药物的联合使用(OR=1.053)和长时间使用抗菌药物(OR=1.100)均为多药耐药菌感染的高危因素(P<0.05)。结论临床应合理使用抗菌药物,要严格执行无菌技术操作的同时还要严格执行手卫生,避免交叉感染,可以减少多药耐药菌感染。
OBJECTIVE To analyze the risk factors of muhidrug-：resistant bacteria infections in the patients of obstetrics and gynecology department so as to formulate the intervention measures for the control of multidrug-resistant bacteria infections. METHODS A total of 132 cases of patients who were treated in the obstetrics and gynecolo- gy department of North Hospital of the Peoplers Hospital of XinjiangUygur Autonomous Region from 2010 to 2013 were enrolled in the study, then the wound culture and drug susceptibility testing were performed for all the patients; 31 patients with multidrug-resistant bacteria infections were assigned as the experimental group, and 101 patients were set as the control groups the age, length of hospitalization, postoperative albumin, white blood cell count, hemoglobin, and use of antibiotics were analyzed, and compared between the two groups. RESULTS Of totally 132 cases of patients, the multidrug-resistant bacteria infections occurred in 31 cases with the infection rate of 23.5 %. The multidrug-resistant Staphylococcus aureus and Escherichia coli were dominant among the multidrugresistant bacteria, accounting for 41.9% and 25.8%, respectively. The incidence of multidrug-resistant bacteria infections was significantly correlated with the type of antibiotic, time of use of antibiotics, postoperative albumin volume, and postoperative while blood cell count（P〈0.05）; the multivariate regression analysis showed that the combination use of antibiotics （OR=1. 053） and long term use of antibiotics （OR=1. 100） were the high risk factors for the multidrug-resistant bacteria infections. CONCLUSION It is necessary for the hospital to reasonably use antibiotics, strictly implement the aseptic technique procedures, and perform the hand hygiene so as to prevent cross infections as well as the multirug-resistant bacteria infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第18期4572-4573,4576,共3页
Chinese Journal of Nosocomiology
基金
天津市科技计划项目(07ZCGYSF02800)
关键词
妇产科
多药耐药菌
感染
高危因素
Obstetrics and gynecology department
Multidrug-resistant bacteria infection
High risk factor
