摘要
目的分析血清C-反应蛋白(CRP)水平在老年不同病原菌肺部感染中的诊断作用。方法对医院的98例社区获得性肺炎(CAP)、128例医院获得性肺炎(HAP)住院患者血中CRP、白细胞(WBC)、中性粒细胞(N)进行测定,并对痰标本进行病原菌分离鉴定。结果 CAP、HAP患者血中CRP水平分别为(79.8±16.2)mg/L和(46.4±8.4)mg/L,两组间差异有统计学意义(P<0.01),而WBC、N则无明显差异;CAP患者病原菌检出率为43.88%,以革兰阳性球菌为主占27.55%,HAP患者病原菌检出率为63.28%,以革兰阴性杆菌为主占56.25%,两组患者的病原菌检出率、构成比差异均有统计学意义(P<0.01)。结论 CAP患者CRP水平显著高于HAP患者,两组患者感染的病原菌存在显著性差异,测定CRP水平有助于区分两组患者,指导临床合理选用抗菌药物。
OBJECTIVE To analyze the value of serum C-reactive protein（CRP） level in diagnosis of pulmonary in- fections in the senile patients. METHODS Totally 98 hospitalized patients with community-acquired pneumonia （CAP） and 128 patients with hospital-acquired pneumonia（HAP） were enrolled in the study, then the ratio of CRP, white blood count （WBC）, and neutrophil （N） was determined, and the identification of pathogens isolated from the sputum specimens was performed. RESULTS The level of serum CRP was （79.8±16.2） mg/L in the CAP patients, （46.4±8.4）mg/L in the HAP patients, the difference between the two groups was significant （P 〈0.01）, while the difference in the WBC or N was not significant. The detection rate of pathogens causing CAP was 43.88%, the gram-positive cocci accounted for 27.55% ; the detection rate of the pathogens causing HAP was 63.28%, the gram-negative bacilli accounted for 56.25% ; the difference in the detection rate of pathogens or the constituent ratio between the two groups was significant（P〈0.01）. CONCLUSION The level of CRP in the CAP patients is significant higher than that in the HAP patients,and there is significant difference in the constituent ratio of pathogens between the two groups of patients＇ the determination of level of CRP can help distinguish the CAP patients from the HAP patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第18期4384-4385,共2页
Chinese Journal of Nosocomiology
基金
总后卫生部保健局资助课题(B2000)
关键词
社区获得性肺炎
医院获得性肺炎
C-反应蛋白
Community-acquired pneumonia
Hospital-acquired pneumonia
C-reactive protein
