摘要
目的探讨血液病患者医院获得性肺炎(HAP)病原菌分布特点及对原发血液病的风险和影响,以采取有效的控制措施。方法对近5年医院36例血液病并发医院获得性肺炎的患者进行回顾性调查分析研究。结果 HAP发生在恶性血液肿瘤化疗后的骨髓抑制粒细胞缺乏期19例,免疫性血液病使用糖皮质激素2周后7例;病原菌以革兰阴性杆菌为主,占75.0%;合并HAP的急性白血病患者治疗有效率分别为急性淋巴细胞白血病66.7%,急性非淋巴细胞白血病62.5%;5例患者死于医院获得性肺炎,死亡率13.9%。结论医院获得性肺炎影响血液病患者原发病的康复,对血液病患者的医院获得性肺炎应以预防为主,采取综合性措施予以控制。
OBJECTIVE To investigate the primary bacteria distribution and the risk impact of hematologic patients with hospital-acquired pneumonia（HAP） diseases,in order to take effective control measures.METHODS A retrospective study was carried out to investigate the 36 patients with hematological diseases combined with hospital-acquired pneumonia（HAP） diseases in the past 5 years.RESULTS Totally 19 cases of malignant hematologic patients occurred HAP at bone marrow suppression after chemotherapy agranulocytosis period;7 cases of immune hematologic patients in 2 weeks after using glucocorticoids.Gram-negative bacteria pathogens,accounting for 75.0%.The effective rate of HAP combined with acute leukemia in acute lymphocytic leukemia with 66.7%,62.5% in acute non-lymphocytic leukemia.5 cases were dead for hospital-acquired pneumonia with the mortality of 13.9%.CONCLUSION Hospital-acquired pneumonia can affect the recovery of the patients with primary diseases.The hematological patients on hospital-acquired pneumonia should be based on the prevention,and the comprehensive measures should be adopted to control the hospital-acquired pneumonia.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第2期254-255,共2页
Chinese Journal of Nosocomiology
关键词
血液病
医院获得性肺炎
分析
Hematological diseases
Hospital-acqured pneumonia
Analysis
