摘要
目的观察清热化痰合剂联合西药治疗慢性阻塞性肺病(Chronic Obstructive Pulmonary Diseases,COPD)急性加重期痰热壅肺型的临床疗效。方法将80例急性加重期痰热壅肺型COPD患者完全随机分为治疗组、对照组各40例,给予药物治疗14 d,观察比较两组患者治疗前后的中医症状、血常规、血气分析、肺功能变化。结果治疗组临床疗效明显优于对照组,差异有统计学意义(P<0.05);治疗组中医证候积分明显优于对照组(P<0.01);两组患者血常规、血气分析、肺功能均有所改善,且治疗组优于对照组(P<0.01)。结论清热化痰合剂联合西药可有效改善急性加重期痰热壅肺型COPD患者临床的症状及体征,显著改善患者血常规、血气分析、肺功能结果,提高患者的生存质量。
Objective To observe the clinical efficacy on acute exacerbation of COPD （chronic ob- structive pulmonary diseases）differentiated as blockage of phlegm and heat in the lung pattern/syndrome and treated with Qingre Huatan Mixture and western medicine. Methods Eighty cases of acute exacerbation of COPD differentiated as blockage of phlegm and heat in the lung pattern/syndrome were randomized into a treatment group and a control group ,40 cases in each one. The medication was used for 14 days. The changes in TCM symptoms, blood routine results, blood gas analysis and pulmonary analysis were observed and com- pared before and after treatment in the two groups. Results The clinical efficacy in the treatment group was superior obviously to the control group, indicating the significant difference （ P 〈 0.05 ）. The score of TCM pattern/syndrome in the treatment group was obviously better than that in the control group（ P 〈 0.01 ）. The results of blood routine test, blood gas analysis and pulmonary analysis were improved in the patients of the two groups. The results in the treatment group were better than those in the control group （P 〈 0. 01 ）. Con-clusion Qingre Huatan Mixture and western medicine relieve effectively the clinical symptoms and physical signs of the patients of acute exacerbation of COPD differentiated as blockage of phlegm and heat in the lung pattern/syndrome. The combined medication improves significantly the results of blood routine test, blood gas analysis and pulmonary analysis, as well as the survival quality of patients.
出处
《世界中西医结合杂志》
2013年第9期936-939,共4页
World Journal of Integrated Traditional and Western Medicine
基金
山东省中医药科技发展计划项目(No.2011-111)
