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罗哌卡因用于气管表面麻醉预防气管插管反应的效果 被引量:4

Observing the preventive effect of intubation rreaction by intratracheal surface anesthesia with ropivacaine
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摘要 目的 比较罗哌卡因与利多卡因预防气管插管反应的有效性.方法 ASAⅠ~Ⅱ级患者60例,随机分为两组,气管插管前组Ⅰ、组Ⅱ分别使用2%利多卡因及1%罗哌卡因进行气管内表面麻醉,监测麻醉诱导前1分钟、诱导时、诱导后1分钟、气管插管即刻、气管插管后1 分钟、2分钟、3分钟、4 分钟、5分钟血压、心率.结果 与诱导前比较,两组患者插管后收缩压、舒张压、平均动脉压均明显下降,但与插管时比较无明显变化.组Ⅰ心率在插管后4分钟、5分钟时较诱导前下降,插管后2分钟、3分钟时较插管时有所上升,组Ⅱ心率在插管后4分钟、5分钟时较插管时下降,组间各时间点血压、心率比较差异无显著性.结论 1%罗哌卡因用于气管内表面麻醉与2%利多卡因均可有效预防气管插管反应. Objective To compare the effect of ropivacaine with lidiocaine in preventing tracheal intubation reaction. Method 60 cases with ASA Ⅰ-Ⅱ were randomly divided into 2 groups, group I with 2% lidiocaine and group ]] with 1% ropivacaine for trachea topical surface anesthesia before endotracheal intubation. The blood pressure, heart rate were recorded at the time points of I min before induction, induction, 1 rain after induction, intubation, 1 min ,2 rain ,3 min ,4 rain ,5 min after intubation. Result SBP, DBP, MBP were all decreased obviously (P〈0.05) at the time point of intubation and after intubation comparing with which of before induction, but no significant difference was found when comparing with intubation. HR decreased significantly at 4,5 min after intubation camparing with 1 min before induction and increased significantly at 2,3 min after intubation camparing with intubation in group Ⅰ , HR decreased significantly at 4,5 min after intubation camparing to intubation in group Ⅱ , there's no significant diffenence in SBP, DBP, MBP and HR between group Ⅰ and group Ⅱ at all the time points. Conclusion Trachea topical surface anesthesia using 1% ropivacaine has the same preventive effect as 2% lidiocaine in intubation reaction.
出处 《中国医刊》 CAS 2013年第9期30-31,共2页 Chinese Journal of Medicine
关键词 罗哌卡因 利多卡因 气管表面麻醉 插管反应 Ropivacaine Lidiocaine Trachea topical surface anesthesia Intubation reaction
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