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血清AFU和AFP联合检测在原发性肝癌诊断中的意义 被引量:13

The significance of serum AFP and AFU combined measurements in the diagnosis of primary hepatic carcinoma
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摘要 目的探讨血清a-L-岩藻糖苷酶(AFU)和甲胎蛋白(AFP)联合检测对原发性肝癌诊断的指导作用。方法分别测定68例原发性肝癌、79例肝脏良性病变者、72例肝外恶性肿瘤患者和100例健康体检者血清AFU和AFP水平,并进行统计学分析。结果血清AFU和AFP水平,健康对照组明显低于原发性肝癌组(P<0.05);原发性肝癌组异常检出率也较高(P<0.01);AFU和AFP联合检测可提高原发性肝癌的阳性检出率。结论血清AFU和AFP的联合检测可提高对原发性肝癌诊断的灵敏度。 Objective To investigate the directive function of combined measurements of serum AFP and AFU in the diagnosis of primary hepatic carcinoma.Methods 68 cases of primary liver cancer,79 cases of liver benign lesions,72 cases of the patients with other malignant tumors and 100 cases of healthy individuals were enrolled in the study,for whom the serum levels of AFU and AFP were measured.Results Serum AFU and AFP levels of health-control group was lower than that of primary liver-cancer group(P&lt;0.05);Abnormal detection rates was higher in primary liver-cancer group(P&lt;0.01);combined measurements of AFU and AFP could increase the positive detection rate of primary liver cancer(83.2%).Conclusion The combined measurements of serum levels of AFP and AFU improves the diagnostic sensitivity for primary hepatic cancer.
出处 《国际检验医学杂志》 CAS 2013年第16期2093-2094,共2页 International Journal of Laboratory Medicine
关键词 肝肿瘤 甲胎蛋白类 Α-L-岩藻糖苷酶 liver neoplasms alpha-fetoproteins alpha-L-fucosidase
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