摘要
越来越多的实验结果证实肿瘤起源于干细胞,诸如白血病、乳腺癌、脑肿瘤等已成功分离出肿瘤干细胞,有关肝干细胞与肝癌的研究较为成熟,理论上应存在肝癌干细胞,但因缺乏特异性标志物,相关的肝癌干细胞分离尚未成功。
There are increasing research data to support the hypothesis that tumor is originated from its stem cell. Specific bio-marker of tumor stem cells （TSCs） had been successfully isolated in leukemia, breast cancer, brain tumor and some other types of tumor. There were intensive studies focused on defining the hepatic stem cell and its relation with hepatocellular carcinoma （HCC） since long time and interesting progress had been made. But since now, hepatoma stem cell had not been successfully isolated because lack of the specific bio-marker even theoretically there might he. Here, we reviewed and summarized recent published data and research progress focusing on the stem cell and tu- morigenesis study, also our understanding and perspectives.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2007年第16期957-960,共4页
Chinese Journal of Clinical Oncology
基金
国家自然科学基金(编号:30370341
30570410)
全国优秀博士专项基金资助(编号:200261)
关键词
干细胞
肿瘤干细胞
肝细胞癌
癌发生
Stem cell Tumor stem cell Hepatocellular carcinoma Carcinogenesis
