摘要
目的观察补肾健脾通便颗粒治疗脾肾阳虚型慢性功能性便秘的临床疗效。方法将航天中心医院中医科2010年11月至2013年1月收治的60例慢性功能性便秘患者依据随机数字表法分为两组:试验组(30例)采用自拟补肾健脾通便颗粒治疗,对照组(30例)采用乳果糖口服溶液治疗。观察两组患者的Bristol粪便性状评分、平均每周排便频率评分、平均每次排便时间评分及脾肾阳虚证候积分。结果试验组慢性功能性便秘患者在Bristol粪便性状分型与评分、平均每周排便频率评分、腹中冷痛治疗前后的症状积分改善方面优于对照组(P<0.05);治疗4周后,试验组慢性功能性便秘患者的临床疗效显著优于对照组(P=0.019),且两组患者服药后均无不良事件发生。结论补肾健脾通便颗粒治疗脾肾阳虚型慢性功能性便秘具有临床疗效显著、安全经济、方法简便的优势。
Objective To study clinical effect of Bushen-jianpi-tongbian herbs for treating chronic functional constipation.Methods Sixty patients with confirmed diagnosis of chronic functional constipation treated by Traditional Chinese Medicine Department of Aerospace Centre Hospital from November 2010 to January 2013 were randomly assigned to 2 groups.The patients in trial group(30 cases) were treated with bushen-jianpi-tongbian Herbs,while the other patients in control group(30 cases) were treated with duphalac.Bristol stool score,average weekly stool frequency score,the average time of each defecation scores and spleen deficiency syndrome score of the two groups were observed.Results Compared with the control group,symptoms such as each week defecate frequency,change of the defecate characters,cold pain in the abdomen and so on are improved more apparently in the trial group(P 0.05).4 weeks after treatment,the clinical efficacy for chronic functional constipation of the trial groupwas significantly better than the control group(P = 0.019).No adverse event occurred during the treatment course in both groups.Conclusion Bushen-jianpi-tongbian herbs for treating chronic functional constipation has the advantages of significant clinical effect,high safety,economical and simple use.
出处
《医学综述》
2013年第16期3061-3063,共3页
Medical Recapitulate
关键词
中医
慢性功能性便秘
补肾健脾通便颗粒
Traditional chinese medicine
Chronic functional constipation
Bushen-jianpi-tongbian herbs