摘要
【目的】探讨复方丹参滴丸对中青年脑卒中患者D-二聚体及同型半胱氨酸（Hcy）的影响。【方法】选择经头颅CT或核磁共振检查证实为脑卒中的青年患者137例，随机分为两组：观察组69例，采用复方丹参滴丸、丁苯酞氯化钠与阿司匹林治疗；对照组68例，仅采用苯酞氯化钠与阿司匹林治疗。比较两组患者急性期与恢复期的血清D-二聚体和Hcy水平。【结果】经治疗后，两组患者D-2-聚体与Hcy水平呈降低趋势（P〈O．05）；在急性期和康复期治疗组患者血清D-二聚体与Hcy水平均低于对照组，差异有统计学意义（P〈0．05）。【结论】复方丹参滴丸可改善脑卒中患者的血液高凝状态，具有抗血栓、降低D-二聚体及Hcy水平的作用。
[Objective]To explore the impact of compound Danshen drip pill（CSDP） on D-dimer and homo- cysteine（Hcy） in young patients with stroke. [Methods]Totally 137 patients with stroke confirmed by cerebral CT or MRI were chosen and divided into two groups. The observation group（ n =69） was treated with CSDP, butylphthalide NaCl and aspirin. The control group（ n = 68）was only treated with butylphthalide NaC1 and aspirin. Serum levels of D-dimer and Hcy in patients during acute and rehabilitation period were compared be- tween two groups. [Results]After treatment, the levels of D-dimer and Hcy in two groups showed a decreasing trend（ P d0. 05）. In acute phase and rehabilitation period, serum levels of D-dimer and Hcy in treatment group were lower than those in control group, and there was significant difference（ P d0.05）. [Conclusion] CSDP can improve hypercoagulable state of patients with stroke, and has the effects such as anti-thrombosis and lowering the levels of D-dimer and Hcy.
出处
《医学临床研究》
CAS
2013年第8期1497-1498,1502,共3页
Journal of Clinical Research
关键词
卒中
丹参
半胱氨酸
Stroke
Salvia miltiorrhiza
Cysteine
