摘要
随着社会老龄化进程的不断加快,人们的生活方式也在相应的发生变化,高龄患者由于身体机能下降,在日常活动中常容易发生髋部骨折,其基础原因是骨质疏松,多属于脆性骨折,术前充分检查和全身各系统功能的评估非常重要,围手术期的处理是手术成功的关键,手术成败相当一部分因素依赖于内科疾病的处理。临床上髋部骨折手术治疗中的心脑卒中发生率也不断增加,尤其是高龄患者,常并存有多种内科疾病,多数脏器功能储备较低,耐受麻醉、手术等应激的能力较差,患者在围手术期的创伤应激状态下,极易引发脑卒中等心脑血管疾病,临床治疗中应加强对高龄髋部骨折患者围手术期的心脑卒中预防措施。丹参川穹嗪注射液能够降低抗血小板的聚集功能,使冠状动脉、脑血管得以扩张,降低血液粘稠程度,提高红细胞的流动速率,改善微循环情况,有效防止心肌缺血、心肌梗死或脑梗死的发生。本文主要对近几年来丹参川穹嗪在高龄髋部骨折患者围手术期心脑卒中治疗中的应用做一综述,旨在为临床研究提供相关参考价值。
With the accelerating process of aging society,people＇s life style is changing accordingly,elderly patients due to physical decline in daily activities,often prone to hip fracture,its basic reason is osteoporosis,which belongs to brittle fracture,evaluation of preoperative examination and the systemic function is very important.Perioperative treatment is the key to the success of surgery treatment,a considerable part of the success of surgery depends on the factors of internal diseases.The incidence of cardio cerebral stroke in hip fracture surgery is also increasing,especially in elderly patients,often and there are a variety of medical diseases,the majority of organ function reserve is low,tolerance to anesthesia,surgery and other stress ability is poor,Patients in the perioperative period of traumatic stress,easily lead to stroke secondary cardiovascular disease,in clinical treatment,we should strengthen the prevention measures of perioperative stroke in elderly patients with hip fracture,Salvia miltiorrhiza ligustrazine injection can effectively prevent the occurrence of myocardial ischemia,myocardial infarction,or cerebral infarction by reducing platelet aggregation function and blood viscous degree,expanding coronary artery,cerebrovascular,improving the flow rate of red blood cells and microcirculation.In this paper mainly for Salvia miltiorrhiza ligustrazine in recent years in elderly hip fracture patients perioperative cardio cerebral apoplexy therapy application review to provide some reference value for clinical research.
出处
《中国生化药物杂志》
CAS
2017年第2期320-322,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
丹参川穹嗪
高龄患者
髋部骨折
脑卒中
Salvia miltiorrhiza ligustrazine
elderly patients
hip fracture
stroke
