摘要
目的观察原发性高血压心功能不全患者血浆NT-BNP浓度,探讨其在原发性高血压心功能不全诊断及预后中的价值。方法用ELISA法测定200例原发性高血压患者血浆NT-BNP浓度,并按照心功能不全的程度分组比较。结果随着心功能不全的程度的加重,血浆NT-BNP浓度明显升高,各组间均有统计学意义(P<0.05);而血浆NT-BNP浓度的升高,心功能恶化及死亡率也明显增加(P<0.05);结论原发性高血压患者发生心功能不全时NT-BNP浓度明显升高,并随着心功能不全程度的加重而升高,是评价心功能的一项敏感指标,与其预后有较好的相关性。
Objective To observe the plasma concentration of BNP of essential hypertention and discuss the valuation of the diagnosis and prognosis of essential hypertention. Methods ELISA assay the plasma concentration of BNP of 200 essential hypertention patients, compare with varying degrees heart failure. Results With the aggravation of heart fail- ure, the plasma concentration of BNP rise. there is statistical significance in each groups （ P 〈 0. 05 ）. With the arise of of concentration plasma BNP, heart failure deteriorate and mortality go up （ P 〈 0. 05 ）. Conclusion The arise of heart failure degree, the concentration plasma BNP rise. The level of plasma BNP may be a marke for diagnosis and prognosis patients with heart failure.
出处
《医药论坛杂志》
2013年第8期21-22,共2页
Journal of Medical Forum
