摘要
本文以“平行菌法”结合“精原细胞法”作为筛选模型 ,对小单孢菌 C5 30 8发酵液脂溶部分的活性成分进行研究。分离得到 C5 30 8- B和 C5 30 8- C两个化合物。通过 UV、IR、MS、1 H- NMR、1 3C- NMR及 HMBC等光谱分析 ,确定 C5 30 8- B为 Dynemicin H。 C5 30 8-
A blue compound was isolated from the fermentation broth and mycelia of a Micromonospora strain C530 8by using the methods of parallel- bacteria and spermatogonium as the screening model.C530 8- B and C530 8- C were obtained from the mixture of the extract. By extensive studies of its UV,IR,MS,1H- NMR,13C- NMR and HMBC spectra,the structure of C530 8- B was elucidated. It is Dynemicin H which contains an anthraquinone portion. The chemical name is 9,8,14- [1]buten[1]yl[4 ]ylideneanthra[1,2 - b]benz [f]azocine- 19- carboxylic acid,5,8,9,14,15,16- hexahydro- 1,4 ,6,17- tetrahydroxy- 2 0 - methoxy- 18- methyl- 5, 16- dioxo- ,[8S- ( 8.a,9.a,14.a,17S* ,18R* ) ]- . The structural study of C530 8- C was underway.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2000年第5期333-335,385,共4页
Chinese Journal of Antibiotics
